КФУ. Карточка публикации. p-tert-Butylthiacalix[4]arenes equipped with guanidinium fragments: aggregation, cytotoxicity, and DNA binding abilities?

RUS

- EN
- 中文
- ES

P-TERT-BUTYLTHIACALIX[4]ARENES EQUIPPED WITH GUANIDINIUM FRAGMENTS: AGGREGATION, CYTOTOXICITY, AND DNA BINDING ABILITIES?

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2016

Язык

английский

Авторы, сотрудники КФУ

Осин Юрий Николаевич, автор

Другие авторы

Imatdinov Ilnaz а, автор

Библиографическое описание на языке оригинала

Andrey Galukhin p-tert-Butylthiacalix[4]arenes equipped with guanidinium fragments: aggregation, cytotoxicity, and DNA binding abilities?/ Andrey Galukhin, Ilnaz Imatdinov and Yuri Osin//The Royal Society of Chemistry, RSC Adv., 2016, 6, 32722–32726

Аннотация

Mono-, di- and tetracationic thiacalix[4]arenes in a 1,3-alternate conformation functionalized with guanidinium groups showed a strong dependence of the aggregation properties with the ratio of guanidinium/n-decyl fragments attached to phenolic groups. Increasing the amount of guanidinium fragments improved the macrocycles solubility in water as well as the sorption capacity towards polynucleotide molecules. The synthesized thiacalixarenes showed relatively high toxicity comparable with that for similar receptors based on the classical calixarene.

Ключевые слова

p-tert-Butylthiacalix[4]arenes, guanidinium fragments

Название журнала

RSC Advances

Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку

https://repository.kpfu.ru/?p_id=129947

Файлы ресурса

Название файла	Размер (Мб)	Формат
Galuhin.pdf	0,54	pdf	посмотреть / скачать

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Осин Юрий Николаевич	ru_RU
dc.contributor.author	Imatdinov Ilnaz а	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	Andrey Galukhin p-tert-Butylthiacalix[4]arenes equipped with guanidinium fragments: aggregation, cytotoxicity, and DNA binding abilities?/ Andrey Galukhin, Ilnaz Imatdinov and Yuri Osin//The Royal Society of Chemistry, RSC Adv., 2016, 6, 32722–32726	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=129947	ru_RU
dc.description.abstract	RSC Advances	ru_RU
dc.description.abstract	Mono-, di- and tetracationic thiacalix[4]arenes in a 1,3-alternate conformation functionalized with guanidinium groups showed a strong dependence of the aggregation properties with the ratio of guanidinium/n-decyl fragments attached to phenolic groups. Increasing the amount of guanidinium fragments improved the macrocycles solubility in water as well as the sorption capacity towards polynucleotide molecules. The synthesized thiacalixarenes showed relatively high toxicity comparable with that for similar receptors based on the classical calixarene.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	p-tert-Butylthiacalix[4]arenes	ru_RU
dc.subject	guanidinium fragments	ru_RU
dc.title	p-tert-Butylthiacalix[4]arenes equipped with guanidinium fragments: aggregation, cytotoxicity, and DNA binding abilities?	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU