КФУ. Карточка публикации. Dysbiosis of cultivable aerobic microbiota tightly associated with colon cancer epithelial cells

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DYSBIOSIS OF CULTIVABLE AEROBIC MICROBIOTA TIGHTLY ASSOCIATED WITH COLON CANCER EPITHELIAL CELLS

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2015

Язык

английский

Авторы, сотрудники КФУ

Зеленихин Павел Валерьевич, автор

Ильинская Ольга Николаевна, автор

Соколова Евгения Александровна, автор

Авторы, аспиранты КФУ

Нгуен Тхи Нга, автор

Библиографическое описание на языке оригинала

Siraj Y. Dysbiosis of cultivable aerobic microbiota tightly associated with colon cancer epithelial cells / Y. Siraj, N. Nguen, P. Zelenikhin, E. Sokolova, I. Gataullin, O. Ilinskaya // RJPBCS.- 2015.- V.6.- P.1658-1663.

Аннотация

Modern researches focus on metagenome, metatranscriptome, and metaproteome of microorganisms associated with the incidence of colorectal cancer (CRC). Based on assays of fecal samples, it is difficult to obtain unambiguous conclusion about contribution of certain microorganisms to CRC. Bacteria tightly associated with colon mucosa could provide more data into CRC mechanisms and give a basis of future approaches for microbiota modulation and new therapies development. Here we characterize aerobic cultivable bacteria isolated from biopsy samples of human neoplastic and normal colon epithelia, to compare the spectrum and some physiological features of bacterial habitants of the biological niche, which nearby parts differ on a level of oncogenic transformation. 98 cultured bacterial strains from 28 patients with CRC were isolated, cultivated and identified using MALDI-TOF mass spectrometry. From colon biopsies cultivable Escherichia coli, Serratia marcescens and representatives of the gene

Ключевые слова

colorectal cancer, microflora, antibiotic susceptibility, secreted RNase activity

Название журнала

Research Journal of Pharmaceutical, Biological and Chemical Sciences

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https://repository.kpfu.ru/?p_id=118548

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Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Зеленихин Павел Валерьевич	ru_RU
dc.contributor.author	Ильинская Ольга Николаевна	ru_RU
dc.contributor.author	Соколова Евгения Александровна	ru_RU
dc.contributor.author	Нгуен Тхи Нга	ru_RU
dc.date.accessioned	2015-01-01T00:00:00Z	ru_RU
dc.date.available	2015-01-01T00:00:00Z	ru_RU
dc.date.issued	2015	ru_RU
dc.identifier.citation	Siraj Y. Dysbiosis of cultivable aerobic microbiota tightly associated with colon cancer epithelial cells / Y. Siraj, N. Nguen, P. Zelenikhin, E. Sokolova, I. Gataullin, O. Ilinskaya // RJPBCS.- 2015.- V.6.- P.1658-1663.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=118548	ru_RU
dc.description.abstract	Research Journal of Pharmaceutical, Biological and Chemical Sciences	ru_RU
dc.description.abstract	Modern researches focus on metagenome, metatranscriptome, and metaproteome of microorganisms associated with the incidence of colorectal cancer (CRC). Based on assays of fecal samples, it is difficult to obtain unambiguous conclusion about contribution of certain microorganisms to CRC. Bacteria tightly associated with colon mucosa could provide more data into CRC mechanisms and give a basis of future approaches for microbiota modulation and new therapies development. Here we characterize aerobic cultivable bacteria isolated from biopsy samples of human neoplastic and normal colon epithelia, to compare the spectrum and some physiological features of bacterial habitants of the biological niche, which nearby parts differ on a level of oncogenic transformation. 98 cultured bacterial strains from 28 patients with CRC were isolated, cultivated and identified using MALDI-TOF mass spectrometry. From colon biopsies cultivable Escherichia coli, Serratia marcescens and representatives of the gene	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	colorectal cancer	ru_RU
dc.subject	microflora	ru_RU
dc.subject	antibiotic susceptibility	ru_RU
dc.subject	secreted RNase activity	ru_RU
dc.title	Dysbiosis of cultivable aerobic microbiota tightly associated with colon cancer epithelial cells	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU