| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2008 |
| Язык | английский |
|
Зиятдинова Гузель Камилевна, автор
|
|
Galandova Julia , автор
Labuda Jan , автор
|
| Библиографическое описание на языке оригинала |
Ziyatdinova, G. Impedimetric nanostructured disposable DNA-based biosensors for the detection of deep DNA damage and effect of antioxidants / G. Ziyatdinova, J. Galandova, J. Labuda // Intern. J. Electrochem. Sci. - 2008. - V. 3. - No. 3. - P. 223-235. |
| Аннотация |
Novel impedimetric nanostructured disposable DNA-biosensors have been created using a layer of multiwalled carbon nanotubes (MWNT) and double stranded calf thymus or herring sperm DNA deposited on the surface of a screen-printed carbon electrode (SPCE) by layer-by-layer and mixed coverage. The presence of DNA significantly decreases the electroconductivity of the MWNT/SPCE interface and represents a charge barrier for the transport of the [Fe(CN6)]3- redox probe ions. Hence, electrochemical impedimetric procedure performed with DNA/MWNT/SPCE sensor in 0.1 M phosphate buffer solution (PBS) pH 7.0 using 1 mM [Fe(CN6)]3- was developed for the evaluation of deep DNA damage caused by reactive oxygen species formed in situ as well as antioxidative effects of rutin and tea extracts. |
| Ключевые слова |
Electrochemical impedance spectroscopy, multiwalled carbon nanotubes, DNA
electrochemical biosensor, DNA damage, antioxidants |
| Название журнала |
International Journal of Electrochemical Science
|
| URL |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84866930302&partnerID=40&md5=26c37b25f4f7f7fa506078a5d679d9ee |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=134868 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Зиятдинова Гузель Камилевна |
ru_RU |
| dc.contributor.author |
Galandova Julia |
ru_RU |
| dc.contributor.author |
Labuda Jan |
ru_RU |
| dc.date.accessioned |
2008-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2008-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2008 |
ru_RU |
| dc.identifier.citation |
Ziyatdinova, G. Impedimetric nanostructured disposable DNA-based biosensors for the detection of deep DNA damage and effect of antioxidants / G. Ziyatdinova, J. Galandova, J. Labuda // Intern. J. Electrochem. Sci. - 2008. - V. 3. - No. 3. - P. 223-235. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=134868 |
ru_RU |
| dc.description.abstract |
International Journal of Electrochemical Science |
ru_RU |
| dc.description.abstract |
Novel impedimetric nanostructured disposable DNA-biosensors have been created using a layer of multiwalled carbon nanotubes (MWNT) and double stranded calf thymus or herring sperm DNA deposited on the surface of a screen-printed carbon electrode (SPCE) by layer-by-layer and mixed coverage. The presence of DNA significantly decreases the electroconductivity of the MWNT/SPCE interface and represents a charge barrier for the transport of the [Fe(CN6)]3- redox probe ions. Hence, electrochemical impedimetric procedure performed with DNA/MWNT/SPCE sensor in 0.1 M phosphate buffer solution (PBS) pH 7.0 using 1 mM [Fe(CN6)]3- was developed for the evaluation of deep DNA damage caused by reactive oxygen species formed in situ as well as antioxidative effects of rutin and tea extracts. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Electrochemical impedance spectroscopy |
ru_RU |
| dc.subject |
multiwalled carbon nanotubes |
ru_RU |
| dc.subject |
DNA
electrochemical biosensor |
ru_RU |
| dc.subject |
DNA damage |
ru_RU |
| dc.subject |
antioxidants |
ru_RU |
| dc.title |
Impedimetric nanostructured disposable DNA-based biosensors for the detection of deep DNA damage and effect of antioxidants |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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