КФУ. Карточка публикации. Electrochemical determination of the total antioxidant capacity of human plasma

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ELECTROCHEMICAL DETERMINATION OF THE TOTAL ANTIOXIDANT CAPACITY OF HUMAN PLASMA

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2005

Язык

английский

Авторы, сотрудники КФУ

Будников Герман Константинович, автор

Зиятдинова Гузель Камилевна, автор

Другие авторы

Погорельцев Валерий Ильич, автор

Библиографическое описание на языке оригинала

Ziyatdinova G.K., Budnikov H.C., Pogorel'tzev V.I. Electrochemical determination of the total antioxidant capacity of human plasma // Anal. Bioanal. Chem. - 2005. - V. 381. - No. 8. - P. 1546-1551.

Аннотация

Electrochemical reduction of oxygen at glassy carbon electrode in 0.05 M solution of (C2H5)4NI in dimethylformamide leads to generation of superoxide anion-radical. Product of one-electron reversible oxygen reduction (superoxide anion-radical) reacts with antioxidants. Process is based on the protonation of the anion-radical with antioxidant. Rate constants of this interaction were calculated. Human plasma antioxidants also react with electrochemically generated superoxide anion-radical. The voltammetric method for estimation of plasma?s total antioxidant capacity (TAC) based on this reaction is proposed. Moreover, TAC of plasma was determined using constant-current coulometry with the electrogenerated bromine as active species. There is correlation between TAC data received by voltammetry (О2?- with α-tocopherol units) and coulometry (Br2 as titrant). TAC of plasma from patients with purulent infections was determined.

Ключевые слова

Total antioxidant capacity, voltammetry, superoxide anion-radical, plasma

Название журнала

Analytical and Bioanalytical Chemistry

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-18144393804&partnerID=40&md5=6077157cadac2ea2f4e23d9b7d5e9e03

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https://repository.kpfu.ru/?p_id=134872

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Будников Герман Константинович	ru_RU
dc.contributor.author	Зиятдинова Гузель Камилевна	ru_RU
dc.contributor.author	Погорельцев Валерий Ильич	ru_RU
dc.date.accessioned	2005-01-01T00:00:00Z	ru_RU
dc.date.available	2005-01-01T00:00:00Z	ru_RU
dc.date.issued	2005	ru_RU
dc.identifier.citation	Ziyatdinova G.K., Budnikov H.C., Pogorel'tzev V.I. Electrochemical determination of the total antioxidant capacity of human plasma // Anal. Bioanal. Chem. - 2005. - V. 381. - No. 8. - P. 1546-1551.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=134872	ru_RU
dc.description.abstract	Analytical and Bioanalytical Chemistry	ru_RU
dc.description.abstract	Electrochemical reduction of oxygen at glassy carbon electrode in 0.05 M solution of (C2H5)4NI in dimethylformamide leads to generation of superoxide anion-radical. Product of one-electron reversible oxygen reduction (superoxide anion-radical) reacts with antioxidants. Process is based on the protonation of the anion-radical with antioxidant. Rate constants of this interaction were calculated. Human plasma antioxidants also react with electrochemically generated superoxide anion-radical. The voltammetric method for estimation of plasma?s total antioxidant capacity (TAC) based on this reaction is proposed. Moreover, TAC of plasma was determined using constant-current coulometry with the electrogenerated bromine as active species. There is correlation between TAC data received by voltammetry (О2?- with α-tocopherol units) and coulometry (Br2 as titrant). TAC of plasma from patients with purulent infections was determined.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Total antioxidant capacity	ru_RU
dc.subject	voltammetry	ru_RU
dc.subject	superoxide anion-radical	ru_RU
dc.subject	plasma	ru_RU
dc.title	Electrochemical determination of the total antioxidant capacity of human plasma	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU