| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2016 |
| Язык | английский |
|
Гусев Олег Александрович, автор
Ризванов Альберт Анатольевич, автор
|
| Библиографическое описание на языке оригинала |
Akalabya Bissoyi, Awanish Kumar, Albert A. Rizvanov, et al., “Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells,” Stem Cells International, vol. 2016, Article ID 3604203, 9 pages, 2016. doi:10.1155/2016/3604203 |
| Аннотация |
Mesenchymal Stem Cells (MSCs) are a promising mammalian cell type as they can be used for the reconstruction of human tissues and organs. MSCs are shown to form bone, cartilage, fat, and muscle-like cells under specific cultivation conditions. Current technology of MSCs cryopreservation has significant disadvantages. Alternative technologies of mammalian cells preservation through lyophilisation or desiccation (air-drying) are among the upcoming domains of investigation in the field of cryobiology. Different protectants and their combinations were studied in this context. Loading of the protectant in the live cell can be a challenging issue but recent studies have shown encouraging results. This paper deals with a review of the protectants, methods of their delivery, and physical boundary conditions adopted for the desiccation and lyophilisation of mammalian cells, including MSCs. A hybrid technique combining both methods is also proposed as a promising way of MSCs dry preservation. |
| Ключевые слова |
anhydrobiosis, MSC, dry preservation |
| Название журнала |
Stem Cells International
|
| URL |
http://www.hindawi.com/journals/sci/2016/3604203/abs/ |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=136565 |
| Файлы ресурса | |
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Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Гусев Олег Александрович |
ru_RU |
| dc.contributor.author |
Ризванов Альберт Анатольевич |
ru_RU |
| dc.date.accessioned |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2016 |
ru_RU |
| dc.identifier.citation |
Akalabya Bissoyi, Awanish Kumar, Albert A. Rizvanov, et al., “Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells,” Stem Cells International, vol. 2016, Article ID 3604203, 9 pages, 2016. doi:10.1155/2016/3604203 |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=136565 |
ru_RU |
| dc.description.abstract |
Stem Cells International |
ru_RU |
| dc.description.abstract |
Mesenchymal Stem Cells (MSCs) are a promising mammalian cell type as they can be used for the reconstruction of human tissues and organs. MSCs are shown to form bone, cartilage, fat, and muscle-like cells under specific cultivation conditions. Current technology of MSCs cryopreservation has significant disadvantages. Alternative technologies of mammalian cells preservation through lyophilisation or desiccation (air-drying) are among the upcoming domains of investigation in the field of cryobiology. Different protectants and their combinations were studied in this context. Loading of the protectant in the live cell can be a challenging issue but recent studies have shown encouraging results. This paper deals with a review of the protectants, methods of their delivery, and physical boundary conditions adopted for the desiccation and lyophilisation of mammalian cells, including MSCs. A hybrid technique combining both methods is also proposed as a promising way of MSCs dry preservation. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
anhydrobiosis |
ru_RU |
| dc.subject |
MSC |
ru_RU |
| dc.subject |
dry preservation |
ru_RU |
| dc.title |
Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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