КФУ. Карточка публикации. Semaphorins Are likely to Be Involved in the Control of Hibernation

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SEMAPHORINS ARE LIKELY TO BE INVOLVED IN THE CONTROL OF HIBERNATION

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2017

Язык

английский

Авторы, сотрудники КФУ

Газизова Гузель Рашитовна, автор

Козлова Ольга Сергеевна, автор

Нуруллин Лениз Фаритович, автор

Тяпкина Оксана Викторовна, автор

Шагимарданова Елена Ильясовна, автор

Библиографическое описание на языке оригинала

Gazizova G., Kozlova O., Tyapkina O., Nurullin L., Shagimardanova E. Semaphorins Are likely to Be Involved in the Control of Hibernation // BioNanoSci. (2017). doi:10.1007/s12668-016-0292-z

Аннотация

Hibernation is unique mammals' phenotype demonstrated surviving in seasonal adverse environment conditions. During hibernation, all of systems of organs undergo alterations in their metabolic activity and physiology similar to different physiological conditions associated with human diseases and injuries, which represent a proper model for studying new approaches in clinical treatment. In this study, we have analyzed expression of semaphorins in small hibernator edible dormouse (Glis glis). Semaphorins are factors which involved in a key process of axon guidance and cell–cell communication and can act as tumor suppressor. We found that gene coding Semaphorin-3D (SEMA3D), previously reported to be specific for brain and heart of mammals, represents one of the most upregulated transcripts in the muscles of the hibernating dormice. Furthermore, another member of the same family, Semaphorin-5B (SEMA5B), was strongly induced in the spinal cord of hibernating animals. These observations make

Ключевые слова

Semaphorin, Hibernation, Edible dormice, Gene expression

Название журнала

BioNanoScience

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https://repository.kpfu.ru/?p_id=140066

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Газизова Гузель Рашитовна	ru_RU
dc.contributor.author	Козлова Ольга Сергеевна	ru_RU
dc.contributor.author	Нуруллин Лениз Фаритович	ru_RU
dc.contributor.author	Тяпкина Оксана Викторовна	ru_RU
dc.contributor.author	Шагимарданова Елена Ильясовна	ru_RU
dc.date.accessioned	2017-01-01T00:00:00Z	ru_RU
dc.date.available	2017-01-01T00:00:00Z	ru_RU
dc.date.issued	2017	ru_RU
dc.identifier.citation	Gazizova G., Kozlova O., Tyapkina O., Nurullin L., Shagimardanova E. Semaphorins Are likely to Be Involved in the Control of Hibernation // BioNanoSci. (2017). doi:10.1007/s12668-016-0292-z	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=140066	ru_RU
dc.description.abstract	BioNanoScience	ru_RU
dc.description.abstract	Hibernation is unique mammals' phenotype demonstrated surviving in seasonal adverse environment conditions. During hibernation, all of systems of organs undergo alterations in their metabolic activity and physiology similar to different physiological conditions associated with human diseases and injuries, which represent a proper model for studying new approaches in clinical treatment. In this study, we have analyzed expression of semaphorins in small hibernator edible dormouse (Glis glis). Semaphorins are factors which involved in a key process of axon guidance and cell–cell communication and can act as tumor suppressor. We found that gene coding Semaphorin-3D (SEMA3D), previously reported to be specific for brain and heart of mammals, represents one of the most upregulated transcripts in the muscles of the hibernating dormice. Furthermore, another member of the same family, Semaphorin-5B (SEMA5B), was strongly induced in the spinal cord of hibernating animals. These observations make	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Semaphorin	ru_RU
dc.subject	Hibernation	ru_RU
dc.subject	Edible dormice	ru_RU
dc.subject	Gene expression	ru_RU
dc.title	Semaphorins Are likely to Be Involved in the Control of Hibernation	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU