Казанский (Приволжский) федеральный университет, КФУ
КАЗАНСКИЙ
ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ
 
GENETIC CHARACTERIZATION OF SMALL (S)-SEGMENT GENOME PUUMALA VIRUS STRAIN KAZAN
Форма представленияСтатьи в зарубежных журналах и сборниках
Год публикации2016
  • Ризванов Альберт Анатольевич, автор
  • Кабве Эммануэль , автор
  • Библиографическое описание на языке оригинала Kabwe, E., Davidyuk, N.Y., Morzunov, S.P. et al. Genetic Characterization of Small (s)-Segment Genome Puumala Virus Strain Kazan.BioNanoSci. (2016). doi:10.1007/s12668-016-0338-2
    Аннотация The Republic of Tatarstan is one of the most active endemic regions for nephropathia epidemica (NE) in the Russian Federation. Annually, over 1000 cases of NE are registered, with an average mortality rate of 0.43 %. NE is a zoonosis where human become infected by inhaling a hantavirus-contaminated aerosol. Puumala virus is commonly detected in NE cases. Although NE cases have been registered in the region since 1958, little is known about the genetic variability of Puumala virus circulating in Tatarstan. We conducted phylogenetic analysis of the full length (1828 nt) small (S) segment genome sequence of Puumala virus RNA isolated from four bank voles (Myodes glareolus) captured during the 2014 outbreak. These virus sequences were compared to known sequences of Puumala viruses from nearby regions such as Samara and the Republic of Bashkortostan, as well as to European isolates. We found that there was over 89 % nucleotide identity between Puumala virus sequences isolated from the bank
    Ключевые слова S-segmentPuumala virusHantavirusesBunyaviridaeNephropathia Epidemica (NE)Hemorrhagic fever with renal syndrome (HFRS)
    Название журнала BioNanoScience
    URL http://link.springer.com/article/10.1007/s12668-016-0338-2
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