| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2016 |
| Язык | английский |
|
Зефиров Тимур Львович, автор
Зиятдинова Нафиса Ильгизовна, автор
Купцова Анна Михайловна, автор
|
| Библиографическое описание на языке оригинала |
Kuptsova A.M. CHOLINERGIC REGULATION OF THE DEVELOPING HEART CONTRACTILITY / A.M. Kuptsova, N.I. Ziyatdinova, R.G. Biktemirova, T.L. Zevfirov // International Journal of Pharmacy & Technology. - 2016. - Vol. 8. - Issue No.3 - P. 14999-15007
|
| Аннотация |
The activity of the sympathetic and parasympathetic divisions of the autonomic nervous system changes with aging. The researchers suggest that the changes in the heart activity are associated with the restructuring of the sympatheticparasympathetic interactions of the receptor systems in the heart. Our paper describes periods of postnatal ontogenesis associated with the formation of the sympathetic cardiac innervation. The study was conducted in vitro with the use of Power Lab (AD Instruments,Australia) device on the strips of atrial and ventricular myocardium of rats aged 20,8,6,3 and 1 weeks. The obtained results indicate that in all age groups studied the cholinoreceptor agonist – carbachol,on the background of different concentrations of a non-selective blocker of muscarinic cholinergic receptors – atropine,inhibits the inotropy of the atrial and ventricular myocardium. At the same time,the dynamics of myocardial contractility is age dependent. The findings suggest that during post |
| Ключевые слова |
heart, inotropy, muscarinic cholinergic receptors, postnatal ontogenesis |
| Название журнала |
International Journal of Pharmacy & Technology
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=143150 |
| Файлы ресурса | |
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|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Зефиров Тимур Львович |
ru_RU |
| dc.contributor.author |
Зиятдинова Нафиса Ильгизовна |
ru_RU |
| dc.contributor.author |
Купцова Анна Михайловна |
ru_RU |
| dc.date.accessioned |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2016 |
ru_RU |
| dc.identifier.citation |
Kuptsova A.M. CHOLINERGIC REGULATION OF THE DEVELOPING HEART CONTRACTILITY / A.M. Kuptsova, N.I. Ziyatdinova, R.G. Biktemirova, T.L. Zevfirov // International Journal of Pharmacy & Technology. - 2016. - Vol. 8. - Issue No.3 - P. 14999-15007
|
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=143150 |
ru_RU |
| dc.description.abstract |
International Journal of Pharmacy & Technology |
ru_RU |
| dc.description.abstract |
The activity of the sympathetic and parasympathetic divisions of the autonomic nervous system changes with aging. The researchers suggest that the changes in the heart activity are associated with the restructuring of the sympatheticparasympathetic interactions of the receptor systems in the heart. Our paper describes periods of postnatal ontogenesis associated with the formation of the sympathetic cardiac innervation. The study was conducted in vitro with the use of Power Lab (AD Instruments,Australia) device on the strips of atrial and ventricular myocardium of rats aged 20,8,6,3 and 1 weeks. The obtained results indicate that in all age groups studied the cholinoreceptor agonist – carbachol,on the background of different concentrations of a non-selective blocker of muscarinic cholinergic receptors – atropine,inhibits the inotropy of the atrial and ventricular myocardium. At the same time,the dynamics of myocardial contractility is age dependent. The findings suggest that during post |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
heart |
ru_RU |
| dc.subject |
inotropy |
ru_RU |
| dc.subject |
muscarinic cholinergic receptors |
ru_RU |
| dc.subject |
postnatal ontogenesis |
ru_RU |
| dc.title |
CHOLINERGIC REGULATION OF THE DEVELOPING HEART CONTRACTILITY |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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