| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2016 |
| Язык | английский |
|
Еремеев Антон Александрович, автор
Лавров Игорь Александрович, автор
Федянин Артур Олегович, автор
|
|
Федянин Артур Олегович, автор
|
| Библиографическое описание на языке оригинала |
Fedyanin A.O. Influence of Gravitational Unloading on Titin's Structure in the Rat Hind Limb Muscles / A.O. Fedyanin, A.A. Eremeev, T.V. Baltina, I.A. Lavrov //BioNanoSci. - 2016. - DOI 10.1007/s12668-016-0360-4
|
| Аннотация |
The influences of microgravity lead to development of the muscular atrophy and reduction of the volume of muscle fibers, both slow and fast types, changes of the muscles structure, decrease in a muscular tone, and also endurance and general muscles functionality. This study was designed to investigate the changes of the titin's structure in m.soleusand m.extensor digitorum longusinrat after 7 days ofgravitationalunloading.Electrophysiologicalandimmunological analysis of both muscles was performed after the rats were maintained in antiortostatic position for 7 days. Results suggest that 7 days of gravitational unloading decrease the titin's intact N2A-isoform and increase titin's T2 fragment in m. soleus. At the same time no influence of gravitational unloading was found on titin's N2A-izoform in m. extensor digitorum longus. Titin reduction in m. soleus and not in m. extensor digitorum longus can suggest different mechanisms of adaptation to the gravitational changes.
|
| Ключевые слова |
Gravityunloading, Titin, M.soleus, M.extensor digitorum longus
|
| Название журнала |
BioNanoScience
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=143620 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Еремеев Антон Александрович |
ru_RU |
| dc.contributor.author |
Лавров Игорь Александрович |
ru_RU |
| dc.contributor.author |
Федянин Артур Олегович |
ru_RU |
| dc.contributor.author |
Федянин Артур Олегович |
ru_RU |
| dc.date.accessioned |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2016 |
ru_RU |
| dc.identifier.citation |
Fedyanin A.O. Influence of Gravitational Unloading on Titin's Structure in the Rat Hind Limb Muscles / A.O. Fedyanin, A.A. Eremeev, T.V. Baltina, I.A. Lavrov //BioNanoSci. - 2016. - DOI 10.1007/s12668-016-0360-4
|
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=143620 |
ru_RU |
| dc.description.abstract |
BioNanoScience |
ru_RU |
| dc.description.abstract |
The influences of microgravity lead to development of the muscular atrophy and reduction of the volume of muscle fibers, both slow and fast types, changes of the muscles structure, decrease in a muscular tone, and also endurance and general muscles functionality. This study was designed to investigate the changes of the titin's structure in m.soleusand m.extensor digitorum longusinrat after 7 days ofgravitationalunloading.Electrophysiologicalandimmunological analysis of both muscles was performed after the rats were maintained in antiortostatic position for 7 days. Results suggest that 7 days of gravitational unloading decrease the titin's intact N2A-isoform and increase titin's T2 fragment in m. soleus. At the same time no influence of gravitational unloading was found on titin's N2A-izoform in m. extensor digitorum longus. Titin reduction in m. soleus and not in m. extensor digitorum longus can suggest different mechanisms of adaptation to the gravitational changes.
|
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Gravityunloading |
ru_RU |
| dc.subject |
Titin |
ru_RU |
| dc.subject |
M.soleus |
ru_RU |
| dc.subject |
M.extensor digitorum longus
|
ru_RU |
| dc.title |
Influence of Gravitational Unloading on Titin's Structure in the Rat Hind Limb Muscles |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
EN 
中文 
ES 
Карта сайта
