| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2016 |
| Язык | английский |
|
Аганов Альберт Вартанович, автор
Аганова Оксана Вартановна, автор
Галиуллина Лейсан Фаритовна, автор
Клочков Владимир Васильевич, автор
Латфуллин Ильдус Анварович, автор
|
|
Аганова Оксана Вартановна, автор
|
|
Мусабирова Гузель Салаватовна, автор
|
| Библиографическое описание на языке оригинала |
Galiullina L.F, Aganova O.V, Latfullin I.A, Musabirova G.S., Aganov A.V., Klochkov V.V. NMR Study of Conformational Structure of Fluvastatin and Its Complex with Dodecylphosphocholine Micelles//BioNanoScience. - 2016. - Vol.6, Is.4. - P.352-354. |
| Аннотация |
Fluvastatin is a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. It lowers the overall blood cholesterol level, which is responsible for coronary artery diseases. Conformational features of fluvastatin in water solution were determined. NMR experiments showed that fluvastatin form molecular complex with model cell membrane. It intercalates into membrane surface by its aromatic part. Intermolecular distances between dodecylphosphocholine micelles and fluvastatin nuclei were calculated. |
| Ключевые слова |
Nuclear magnetic resonance, Fluvastatin, Micelles, Molecular complex |
| Название журнала |
BioNanoScience
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=148746 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Аганов Альберт Вартанович |
ru_RU |
| dc.contributor.author |
Аганова Оксана Вартановна |
ru_RU |
| dc.contributor.author |
Галиуллина Лейсан Фаритовна |
ru_RU |
| dc.contributor.author |
Клочков Владимир Васильевич |
ru_RU |
| dc.contributor.author |
Латфуллин Ильдус Анварович |
ru_RU |
| dc.contributor.author |
Мусабирова Гузель Салаватовна |
ru_RU |
| dc.contributor.author |
Аганова Оксана Вартановна |
ru_RU |
| dc.date.accessioned |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2016 |
ru_RU |
| dc.identifier.citation |
Galiullina L.F, Aganova O.V, Latfullin I.A, Musabirova G.S., Aganov A.V., Klochkov V.V. NMR Study of Conformational Structure of Fluvastatin and Its Complex with Dodecylphosphocholine Micelles//BioNanoScience. - 2016. - Vol.6, Is.4. - P.352-354. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=148746 |
ru_RU |
| dc.description.abstract |
BioNanoScience |
ru_RU |
| dc.description.abstract |
Fluvastatin is a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. It lowers the overall blood cholesterol level, which is responsible for coronary artery diseases. Conformational features of fluvastatin in water solution were determined. NMR experiments showed that fluvastatin form molecular complex with model cell membrane. It intercalates into membrane surface by its aromatic part. Intermolecular distances between dodecylphosphocholine micelles and fluvastatin nuclei were calculated. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Nuclear magnetic resonance |
ru_RU |
| dc.subject |
Fluvastatin |
ru_RU |
| dc.subject |
Micelles |
ru_RU |
| dc.subject |
Molecular complex |
ru_RU |
| dc.title |
NMR Study of conformational structure of fluvastatin and its complex with dodecylphosphocholine micelles |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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