Казанский (Приволжский) федеральный университет, КФУ
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EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF PHOSPHONATES BASED ON THE MODEL OF CHRONIC AUTOIMMUNE INFLAMMATION OF THE PAWS OF RATS.
Форма представленияСтатьи в зарубежных журналах и сборниках
Год публикации2016
Языканглийский
  • Зиганшина Лилия Евгеньевна, автор
  • Титаренко Альбина Фаритовна, автор
  • Хазиахметова Вероника Николаевна, автор
  • Библиографическое описание на языке оригинала Valeeva I. Evaluation of Anti-Inflammatory Activity of Phosphonates Based on the Model of Chronic Autoimmune Inflammation of the Paws of Rats. / Valeeva I., Titarenko A., V.Khaziakhmetova, Ziganshina L. // Research Journal of Pharmaceutical, Biological and Chemical Sciences - 2016.- 7(6) - pp.2971-2975.
    Аннотация Currently, there is an ongoing search for new pharmacological agents capable of exhibiting anti-inflammatory properties in the treatment of chronic autoimmune inflammatory diseases of connective tissue of the movable joints, accompanied by progressive violation of motility of the joints, edema and severe pain, developing joint destruction, disability and disability, particularly in rheumatoid arthritis. Based on white laboratory rats experiments in the modeling of chronic autoimmune inflammation of the paws, similar to the clinical course of chronic autoimmune inflammation of the joints of the human by administering Freund's adjuvant the anti-inflammatory effect of dimephosphone, mephopran, ksidiphone has been evaluated. It has been shown that dimephosphone has an anti-inflammatory effect on the model of chronic autoimmune inflammation of rat paws caused by the administration of Freund's adjuvant. Dimethyl ether of 2-carbometoksipropilphosphonic acid (mephoprane) model of adjuvant arth
    Ключевые слова Freund's adjuvant, dimephosphone, monophosphonate - mephopran (dimethyl ether of 2-carbometoksipropilphosphonic acid) ksidiphone (etidronate), prednisolone
    Название журнала Research Journal of Pharmaceutical, Biological and Chemical Sciences
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