| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2017 |
| Язык | английский |
|
Лифанова Анастасия Сергеевна, автор
Ситдикова Гузель Фаритовна, автор
Хаертдинов Наиль Назимович, автор
|
| Библиографическое описание на языке оригинала |
Lifanova A, Khaertdinov N, Sitdikova G., Interplay Between Hydrogen Sulfide and Adrenergic and Muscarinic Receptors in the Mouse Atrium//BioNanoScience. - 2017. - Vol.7, Is.2. - P.306-308. |
| Аннотация |
Hydrogen sulfide (H2S) is synthesized endogenously, and it has a negative inotropic effect on myocardium of different animal species. Interaction between H2S and adrenergic and muscarinic receptors in regulation of mouse atrium contractile function was investigated in this study. Sodium hydrosulfide (NaHS, 300 μM), the H2S donor, decreased the contraction force of atrium. The effect of the H2S donor under β-AR stimulation showed no differences comparison to control values. The agonist of muscarinic receptors carbachol (1 μM) induced a negative inotropic effect and partially prevented the reduction of cardiac muscle contractility by NaHS. Moreover, the effect of carbachol was more pronounced after preliminary application of NaHS. At the same time, after inhibition of β-AR (propranolol, 1 μM) or muscarinic receptors (atropine, 1 μM), negative inotropic effect of NaHS was the same as in control conditions. |
| Ключевые слова |
Hydrogen sulfide (H2S), mouse atrium, muscarinic receptors, β-adrenoceptors |
| Название журнала |
BioNanoScience
|
| URL |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019117734&doi=10.1007%2fs12668-016-0355-1&partnerID=40&md5=2eef48772064895c9895295665193c1a |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=158087 |
| Файлы ресурса | |
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Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Лифанова Анастасия Сергеевна |
ru_RU |
| dc.contributor.author |
Ситдикова Гузель Фаритовна |
ru_RU |
| dc.contributor.author |
Хаертдинов Наиль Назимович |
ru_RU |
| dc.date.accessioned |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2017 |
ru_RU |
| dc.identifier.citation |
Lifanova A, Khaertdinov N, Sitdikova G., Interplay Between Hydrogen Sulfide and Adrenergic and Muscarinic Receptors in the Mouse Atrium//BioNanoScience. - 2017. - Vol.7, Is.2. - P.306-308. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=158087 |
ru_RU |
| dc.description.abstract |
BioNanoScience |
ru_RU |
| dc.description.abstract |
Hydrogen sulfide (H2S) is synthesized endogenously, and it has a negative inotropic effect on myocardium of different animal species. Interaction between H2S and adrenergic and muscarinic receptors in regulation of mouse atrium contractile function was investigated in this study. Sodium hydrosulfide (NaHS, 300 μM), the H2S donor, decreased the contraction force of atrium. The effect of the H2S donor under β-AR stimulation showed no differences comparison to control values. The agonist of muscarinic receptors carbachol (1 μM) induced a negative inotropic effect and partially prevented the reduction of cardiac muscle contractility by NaHS. Moreover, the effect of carbachol was more pronounced after preliminary application of NaHS. At the same time, after inhibition of β-AR (propranolol, 1 μM) or muscarinic receptors (atropine, 1 μM), negative inotropic effect of NaHS was the same as in control conditions. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Hydrogen sulfide (H2S) |
ru_RU |
| dc.subject |
mouse atrium |
ru_RU |
| dc.subject |
muscarinic receptors |
ru_RU |
| dc.subject |
β-adrenoceptors |
ru_RU |
| dc.title |
Interplay Between Hydrogen Sulfide and Adrenergic and Muscarinic Receptors in the Mouse Atrium |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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