| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2018 |
| Язык | английский |
|
Андреева Дина Ивановна, автор
Гумерова Аниса Азатовна, автор
Киясов Андрей Павлович, автор
Титова Ангелина Андреевна, автор
Титова Марина Александровна, автор
|
| Библиографическое описание на языке оригинала |
Kaligin M. Target Cells for Stem Cell Factor in the Adult Islets of Langerhans, Simultaneously Synthesizing Glucagon and Insulin / Kaligin M., Andreeva D., Titova A., Titova M., Gumerova A., Kiyasov A. // BioNanoScience. -2018. - Vol.8, Is.1. - P.296-298. DOI 10.1007/s12668-017-0444-9 |
| Аннотация |
C-kit—a stem cell receptor, or CD117, is one of the
markers of human pancreatic endocrinocyte progenitor cells. Its
important role in the proliferation and differentiation of pancreatic
endocrine cells during human prenatal development has already
been proven. However, the presence and role of c-kit-positive cells
in adult pancreatic islets remains unclear. The purpose of our study
was to establish the presence of c-kit-positive cells in the adult
pancreatic islets and to assess whether they retain the ability to
proliferate during a lifetime. We studied pancreatic autopsies of
adults aged 50 to 70 years, which were obtained in pathology
departments of Kazan hospitals. Samples of the pancreas were
embedded in paraffin using standard techniques. Paraffin sections
of the pancreas were stained immunohistochemically with commercial
antibodies against c-kit, insulin, glucagon, and Ki-67. Few
c-kit-positive cells simultaneously secreting insulin or glucagon
were detected in all samples studi |
| Ключевые слова |
C-kit , CD117, adult pancreatic islets, pancreatic progenitor cells |
| Название журнала |
BioNanoScience
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=162344 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Андреева Дина Ивановна |
ru_RU |
| dc.contributor.author |
Гумерова Аниса Азатовна |
ru_RU |
| dc.contributor.author |
Киясов Андрей Павлович |
ru_RU |
| dc.contributor.author |
Титова Ангелина Андреевна |
ru_RU |
| dc.contributor.author |
Титова Марина Александровна |
ru_RU |
| dc.date.accessioned |
2018-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2018-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2018 |
ru_RU |
| dc.identifier.citation |
Kaligin M. Target Cells for Stem Cell Factor in the Adult Islets of Langerhans, Simultaneously Synthesizing Glucagon and Insulin / Kaligin M., Andreeva D., Titova A., Titova M., Gumerova A., Kiyasov A. // BioNanoScience. -2018. - Vol.8, Is.1. - P.296-298. DOI 10.1007/s12668-017-0444-9 |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=162344 |
ru_RU |
| dc.description.abstract |
BioNanoScience |
ru_RU |
| dc.description.abstract |
C-kit—a stem cell receptor, or CD117, is one of the
markers of human pancreatic endocrinocyte progenitor cells. Its
important role in the proliferation and differentiation of pancreatic
endocrine cells during human prenatal development has already
been proven. However, the presence and role of c-kit-positive cells
in adult pancreatic islets remains unclear. The purpose of our study
was to establish the presence of c-kit-positive cells in the adult
pancreatic islets and to assess whether they retain the ability to
proliferate during a lifetime. We studied pancreatic autopsies of
adults aged 50 to 70 years, which were obtained in pathology
departments of Kazan hospitals. Samples of the pancreas were
embedded in paraffin using standard techniques. Paraffin sections
of the pancreas were stained immunohistochemically with commercial
antibodies against c-kit, insulin, glucagon, and Ki-67. Few
c-kit-positive cells simultaneously secreting insulin or glucagon
were detected in all samples studi |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
C-kit |
ru_RU |
| dc.subject |
CD117 |
ru_RU |
| dc.subject |
adult pancreatic islets |
ru_RU |
| dc.subject |
pancreatic progenitor cells |
ru_RU |
| dc.title |
Target cells for stem cell factor in the adult islets of Langerhans, simultaneously synthesizing glucagon and insulin |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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