КФУ. Карточка публикации. The Effect of High Hydrostatic Pressure on the Viability and Mutagenesis of Salmonella typhimurium

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THE EFFECT OF HIGH HYDROSTATIC PRESSURE ON THE VIABILITY AND MUTAGENESIS OF SALMONELLA TYPHIMURIUM

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2017

Язык

английский

Авторы, сотрудники КФУ

Зеленихин Павел Валерьевич, автор

Ильинская Ольга Николаевна, автор

Карамова Назира Сунагатовна, автор

Киселев Владимир Дмитриевич, автор

Авторы, студенты КФУ

Липатникова Анастасия Александровна, автор

Библиографическое описание на языке оригинала

Karamova, N.S. The Effect of High Hydrostatic Pressure on the Viability and Mutagenesis of Salmonella typhimurium / N.S. Karamova, P.V. Zelenikhin, V.D. Kiselev, A.A. Lipatnikova, O.N. Ilinskaya // Russian Journal of Genetics: Applied Research. - 2017. - V. 7, No. 6. - P. 698–704.

Аннотация

This work is devoted to the study of the influence of high hydrostatic pressure (HHP) on the viability and level of mutagenesis of Salmonella typhimurium. It was established that the viability of bacteria significantly decreases under hydrostatic pressure of 200 MPa or higher. In addition, the viability index of the bacteria is six orders of magnitude lower with respect to the number of colony-forming units (CFUs) compared to the data of the flow cytofluorometry analysis. This is probably due to the transition of some part of the bacterial population to a viable but nonculturable state (VBNC). HHP of 50 MPa caused a 1.9-fold increase in the number of His+ revertants of the S. typhimurium strain TA98, which indicates the potential of the induction of gene mutations under these conditions. The mechanisms to reduce the viability and genetic changes in bacterial cells under HHP conditions are discussed.

Ключевые слова

high hydrostatic pressure, viability, nonculturable state, mutagenesis, mutations, Salmonella typhimurium, flow cytometry, Ames test

Название журнала

Russian Journal of Genetics: Applied Research

URL

https://link.springer.com/article/10.1134/S2079059717060077

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https://repository.kpfu.ru/?p_id=172358

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Зеленихин Павел Валерьевич	ru_RU
dc.contributor.author	Ильинская Ольга Николаевна	ru_RU
dc.contributor.author	Карамова Назира Сунагатовна	ru_RU
dc.contributor.author	Киселев Владимир Дмитриевич	ru_RU
dc.contributor.author	Липатникова Анастасия Александровна	ru_RU
dc.date.accessioned	2017-01-01T00:00:00Z	ru_RU
dc.date.available	2017-01-01T00:00:00Z	ru_RU
dc.date.issued	2017	ru_RU
dc.identifier.citation	Karamova, N.S. The Effect of High Hydrostatic Pressure on the Viability and Mutagenesis of Salmonella typhimurium / N.S. Karamova, P.V. Zelenikhin, V.D. Kiselev, A.A. Lipatnikova, O.N. Ilinskaya // Russian Journal of Genetics: Applied Research. - 2017. - V. 7, No. 6. - P. 698–704.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=172358	ru_RU
dc.description.abstract	Russian Journal of Genetics: Applied Research	ru_RU
dc.description.abstract	This work is devoted to the study of the influence of high hydrostatic pressure (HHP) on the viability and level of mutagenesis of Salmonella typhimurium. It was established that the viability of bacteria significantly decreases under hydrostatic pressure of 200 MPa or higher. In addition, the viability index of the bacteria is six orders of magnitude lower with respect to the number of colony-forming units (CFUs) compared to the data of the flow cytofluorometry analysis. This is probably due to the transition of some part of the bacterial population to a viable but nonculturable state (VBNC). HHP of 50 MPa caused a 1.9-fold increase in the number of His+ revertants of the S. typhimurium strain TA98, which indicates the potential of the induction of gene mutations under these conditions. The mechanisms to reduce the viability and genetic changes in bacterial cells under HHP conditions are discussed.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	high hydrostatic pressure	ru_RU
dc.subject	viability	ru_RU
dc.subject	nonculturable state	ru_RU
dc.subject	mutagenesis	ru_RU
dc.subject	mutations	ru_RU
dc.subject	Salmonella typhimurium	ru_RU
dc.subject	flow cytometry	ru_RU
dc.subject	Ames test	ru_RU
dc.title	The Effect of High Hydrostatic Pressure on the Viability and Mutagenesis of Salmonella typhimurium	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU