| Форма представления | Тезисы и материалы конференций в зарубежных журналах и сборниках |
| Год публикации | 2018 |
| Язык | английский |
|
Гумерова Аниса Азатовна, автор
Киясов Андрей Павлович, автор
Ризванов Альберт Анатольевич, автор
Титова Ангелина Андреевна, автор
Шафигуллина Айгуль Касыймовна, автор
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| Библиографическое описание на языке оригинала |
Shafigullina A. Histochemical analysis of self-organizing 3D spheroid-like cultures of adipose-derived mesenchymal stem cells / A. Shafigullina, A. Titova, A. Rizvanov, A. Gumerova, A. Kiassov // 52nd Annual Scientific Meeting of ESCI, 29 May -1 June 2018, Barcelona, Spain. - European Journal of Clinical Investigation - May, 2018 - Vol.48 (Suppl.1) - P.91. |
| Аннотация |
52nd Annual Scientific Meeting of ESCI, 29 May -1 June 2018, Barcelona, Spain |
| Ключевые слова |
Histochemical analysis, 3D spheroid-like cultures, adipose-derived mesenchymal stem cells, mesenchymal-epithelial transformation, epithelial-mesenchymal transformation |
| Название журнала |
52nd Annual Scientific Meeting of ESCI, 29 May -1 June 2018, Barcelona, Spain
|
| Ссылка для РПД |
http://dspace.kpfu.ru/xmlui/bitstream/handle/net/131560/F_tezis_2_ESCI_2018_final_version.pdf?sequence=2&isAllowed=y
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| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=181997 |
| Файлы ресурса | |
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Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Гумерова Аниса Азатовна |
ru_RU |
| dc.contributor.author |
Киясов Андрей Павлович |
ru_RU |
| dc.contributor.author |
Ризванов Альберт Анатольевич |
ru_RU |
| dc.contributor.author |
Титова Ангелина Андреевна |
ru_RU |
| dc.contributor.author |
Шафигуллина Айгуль Касыймовна |
ru_RU |
| dc.date.accessioned |
2018-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2018-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2018 |
ru_RU |
| dc.identifier.citation |
Shafigullina A. Histochemical analysis of self-organizing 3D spheroid-like cultures of adipose-derived mesenchymal stem cells / A. Shafigullina, A. Titova, A. Rizvanov, A. Gumerova, A. Kiassov // 52nd Annual Scientific Meeting of ESCI, 29 May -1 June 2018, Barcelona, Spain. - European Journal of Clinical Investigation - May, 2018 - Vol.48 (Suppl.1) - P.91. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=181997 |
ru_RU |
| dc.description.abstract |
52nd Annual Scientific Meeting of ESCI, 29 May -1 June 2018, Barcelona, Spain |
ru_RU |
| dc.description.abstract |
Histochemical staining demonstrated fusion of cells with formation of syncytium-like structures. On the periphery cells were polygonal, round, had epithelial morphology. Groups of cells organized in line inside spheroid remained elongated AD-MSC shape. Most of the cells did not proliferate. There were no migrating α SMA+ cells. Polygonal cells on the periphery and a few cells inside the spheroid were desmin+. Interestingly, peripheral and elongated shape cells expressed epithelial marker CK-19+. Probably, within spheroid there was spontaneous mesenchymal-epithelial transdifferentiation. When spheroids were placed in a new culture dish we observed explantational outgrowth of spindle-shaped AD-MSC suggesting that cells within spheroids were alive, able to outgrow and revert through epithelial-mesenchymal transdifferentiation back to MSC phenotype. Investigation was funded by RFBR grant 18-04-01133 and supported by Program of Competitive Growth of KFU. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Histochemical analysis |
ru_RU |
| dc.subject |
3D spheroid-like cultures |
ru_RU |
| dc.subject |
adipose-derived mesenchymal stem cells |
ru_RU |
| dc.subject |
mesenchymal-epithelial transformation |
ru_RU |
| dc.subject |
epithelial-mesenchymal transformation |
ru_RU |
| dc.title |
Histochemical analysis of self-organizing 3D spheroid-like cultures of adipose-derived mesenchymal stem cells |
ru_RU |
| dc.type |
Тезисы и материалы конференций в зарубежных журналах и сборниках |
ru_RU |
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