| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2018 |
|
Ахметзянова Эльвира Руслановна, автор
Галиева Луиза Рамилевна, автор
Гаранина Екатерина Евгеньевна, автор
Закирова Елена Юрьевна, автор
Киясов Андрей Павлович, автор
Костенников Александр Александрович, автор
Мухамедшина Яна Олеговна, автор
Ризванов Альберт Анатольевич, автор
Рогожин Александр Александрович, автор
|
|
Ахметзянова Эльвира Руслановна, автор
|
| Библиографическое описание на языке оригинала |
Mukhamedshina, Y.O., Akhmetzyanova, E.R., Kostennikov, A.A., Zakirova, E.Y.,
Galieva, L.R., Garanina, E.E., Rogozin, A.A., Kiassov, A.P. and Rizvanov, A.A., 2018.
Adipose-Derived Mesenchymal Stem Cell Application Combined With Fibrin Matrix
Promotes Structural and Functional Recovery Following Spinal Cord Injury in
Rats. Frontiers in pharmacology, 9, p.343. |
| Аннотация |
The use of stem and progenitor cells to restore damaged organs and tissues, in particular, the central nervous system, is currently considered a most promising therapy in regenerative medicine. At the same time, another approach aimed at stimulating regeneration with the use of stem cells encapsulated into a biopolymer matrix and capable of creating a specific microenvironment for the implanted cells similar to the natural extracellular matrix is under active development. Here, we study effects of the application of adipose-derived mesenchymal stem cells (AD-MSCs) combined with a fibrin matrix on post-traumatic reactions in the spinal cord in rats. The AD-MSC application is found to exert a positive impact on the functional and structural recovery after spinal cord injury (SCI) that has been confirmed by the results of behavioral/electrophysiological and morphometric studies demonstrating reduced area of abnormal cavities and enhanced tissue retention in the site of injury. |
| Ключевые слова |
spinal cord injury, mesenchymal stem cells, adipose tissue, fibrin matrix, rats |
| Название журнала |
FRONTIERS IN PHARMACOLOGY
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=186322 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Ахметзянова Эльвира Руслановна |
ru_RU |
| dc.contributor.author |
Галиева Луиза Рамилевна |
ru_RU |
| dc.contributor.author |
Гаранина Екатерина Евгеньевна |
ru_RU |
| dc.contributor.author |
Закирова Елена Юрьевна |
ru_RU |
| dc.contributor.author |
Киясов Андрей Павлович |
ru_RU |
| dc.contributor.author |
Костенников Александр Александрович |
ru_RU |
| dc.contributor.author |
Мухамедшина Яна Олеговна |
ru_RU |
| dc.contributor.author |
Ризванов Альберт Анатольевич |
ru_RU |
| dc.contributor.author |
Рогожин Александр Александрович |
ru_RU |
| dc.contributor.author |
Ахметзянова Эльвира Руслановна |
ru_RU |
| dc.date.accessioned |
2018-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2018-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2018 |
ru_RU |
| dc.identifier.citation |
Mukhamedshina, Y.O., Akhmetzyanova, E.R., Kostennikov, A.A., Zakirova, E.Y.,
Galieva, L.R., Garanina, E.E., Rogozin, A.A., Kiassov, A.P. and Rizvanov, A.A., 2018.
Adipose-Derived Mesenchymal Stem Cell Application Combined With Fibrin Matrix
Promotes Structural and Functional Recovery Following Spinal Cord Injury in
Rats. Frontiers in pharmacology, 9, p.343. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=186322 |
ru_RU |
| dc.description.abstract |
FRONTIERS IN PHARMACOLOGY |
ru_RU |
| dc.description.abstract |
The use of stem and progenitor cells to restore damaged organs and tissues, in particular, the central nervous system, is currently considered a most promising therapy in regenerative medicine. At the same time, another approach aimed at stimulating regeneration with the use of stem cells encapsulated into a biopolymer matrix and capable of creating a specific microenvironment for the implanted cells similar to the natural extracellular matrix is under active development. Here, we study effects of the application of adipose-derived mesenchymal stem cells (AD-MSCs) combined with a fibrin matrix on post-traumatic reactions in the spinal cord in rats. The AD-MSC application is found to exert a positive impact on the functional and structural recovery after spinal cord injury (SCI) that has been confirmed by the results of behavioral/electrophysiological and morphometric studies demonstrating reduced area of abnormal cavities and enhanced tissue retention in the site of injury. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
spinal cord injury |
ru_RU |
| dc.subject |
mesenchymal stem cells |
ru_RU |
| dc.subject |
adipose tissue |
ru_RU |
| dc.subject |
fibrin matrix |
ru_RU |
| dc.subject |
rats |
ru_RU |
| dc.title |
Adipose-Derived Mesenchymal Stem Cell Application Combined With Fibrin Matrix
Promotes Structural and Functional Recovery Following Spinal Cord Injury in
Rats. |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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