| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2017 |
|
Ахметзянова Эльвира Руслановна, автор
Галиева Луиза Рамилевна, автор
Закирова Елена Юрьевна, автор
Костенников Александр Александрович, автор
Мухамедшина Яна Олеговна, автор
Ризванов Альберт Анатольевич, автор
|
|
Ахметзянова Эльвира Руслановна, автор
|
| Библиографическое описание на языке оригинала |
Mukhamedshina, Y.O., Zakirova, E.Y., Galieva, L.R., Kostennikov, A.A.,
Akhmetzyanova, E.R. and Rizvanov, A.A., 2017. Distribution and survival of
transplanted adipose-derived mesenchymal stem cells in the spinal cord
injury. BioNanoScience, 7(4), pp.608-612. |
| Аннотация |
Current expectations for successful treatment of
post-traumatic disorders in the CNS are associated with cellbased
technologies. Mesenchymal stem cells, which are under
intensive study, appear to be the most promising. At the same
time, mechanisms of their effect on post-traumatic regeneration
of the spinal cord and their behavior and migration properties in
neurodegenerative lesions are not investigated in full. In our
study, we investigated the survival, migration, and phenotypic
characteristics of a fibrin matrix enclosed in adipose-derived
mesenchymal stem cells (AD-MSCs) by implanting them in
an area of the spinal cord injury in a subacute period. We
showed that adipose-derived mesenchymal stem cells retain
their viability in the area of SCI for up to 60 days and migrate
rostrally and caudally for more than 5 mm. Phenotyping of ADMSCs
in the spinal cord injury area performed on the seventh
day post-transplantation shows that Thy-1, CD 73, and Stro-1
are expressed; however, no CD 4 |
| Ключевые слова |
Adipose-derived mesenchymal stem cells . Spinal
cord injury . Migration |
| Название журнала |
BioNanoScience
|
| URL |
DOI 10.1007/s12668-017-0440-0 |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=186328 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Ахметзянова Эльвира Руслановна |
ru_RU |
| dc.contributor.author |
Галиева Луиза Рамилевна |
ru_RU |
| dc.contributor.author |
Закирова Елена Юрьевна |
ru_RU |
| dc.contributor.author |
Костенников Александр Александрович |
ru_RU |
| dc.contributor.author |
Мухамедшина Яна Олеговна |
ru_RU |
| dc.contributor.author |
Ризванов Альберт Анатольевич |
ru_RU |
| dc.contributor.author |
Ахметзянова Эльвира Руслановна |
ru_RU |
| dc.date.accessioned |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2017 |
ru_RU |
| dc.identifier.citation |
Mukhamedshina, Y.O., Zakirova, E.Y., Galieva, L.R., Kostennikov, A.A.,
Akhmetzyanova, E.R. and Rizvanov, A.A., 2017. Distribution and survival of
transplanted adipose-derived mesenchymal stem cells in the spinal cord
injury. BioNanoScience, 7(4), pp.608-612. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=186328 |
ru_RU |
| dc.description.abstract |
BioNanoScience |
ru_RU |
| dc.description.abstract |
Current expectations for successful treatment of
post-traumatic disorders in the CNS are associated with cellbased
technologies. Mesenchymal stem cells, which are under
intensive study, appear to be the most promising. At the same
time, mechanisms of their effect on post-traumatic regeneration
of the spinal cord and their behavior and migration properties in
neurodegenerative lesions are not investigated in full. In our
study, we investigated the survival, migration, and phenotypic
characteristics of a fibrin matrix enclosed in adipose-derived
mesenchymal stem cells (AD-MSCs) by implanting them in
an area of the spinal cord injury in a subacute period. We
showed that adipose-derived mesenchymal stem cells retain
their viability in the area of SCI for up to 60 days and migrate
rostrally and caudally for more than 5 mm. Phenotyping of ADMSCs
in the spinal cord injury area performed on the seventh
day post-transplantation shows that Thy-1, CD 73, and Stro-1
are expressed; however, no CD 4 |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
|
ru_RU |
| dc.title |
Distribution and survival of
transplanted adipose-derived mesenchymal stem cells in the spinal cord
injury |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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