КФУ. Карточка публикации. Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series

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SYNTHESIS AND ANTIFUNGAL ACTIVITY OF β-HYDROXYSULFIDES OF 1,3-DIOXEPANE SERIES

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2018

Язык

английский

Авторы, сотрудники КФУ

Гнездилов Олег Иванович, автор

Павельев Роман Сергеевич, автор

Чмутова Галина Алексеевна, автор

Библиографическое описание на языке оригинала

Pavelyev R.S, Vafina R.M, Balakin K.V, Synthesis and Antifungal Activity of ? -Hydroxysulfides of 1,3-Dioxepane Series//Journal of Chemistry. - 2018. - Vol.2018, Is.. - Art. № 3589342.

Аннотация

Synthesis of β-hydroxysulfides of 1,3-dioxepane series and their further functionalization were performed. Chiral β-hydroxysulfides were separated into enantiomers using enzymatic acylation by lipase PS. Study of antifungal activity of the obtained compounds showed that some enantiomerically pure 6-arylthio-1,3-dioxepan-5-ols represent promising antifungal drug candidates.

Ключевые слова

β-Hydroxysulfides, organic synthesis, antifungal activity

Название журнала

Journal of Chemistry

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056595073&doi=10.1155%2f2018%2f3589342&partnerID=40&md5=6ec0272009549c9215b26140e65eff8b

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https://repository.kpfu.ru/?p_id=190853

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Гнездилов Олег Иванович	ru_RU
dc.contributor.author	Павельев Роман Сергеевич	ru_RU
dc.contributor.author	Чмутова Галина Алексеевна	ru_RU
dc.date.accessioned	2018-01-01T00:00:00Z	ru_RU
dc.date.available	2018-01-01T00:00:00Z	ru_RU
dc.date.issued	2018	ru_RU
dc.identifier.citation	Pavelyev R.S, Vafina R.M, Balakin K.V, Synthesis and Antifungal Activity of ? -Hydroxysulfides of 1,3-Dioxepane Series//Journal of Chemistry. - 2018. - Vol.2018, Is.. - Art. № 3589342.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=190853	ru_RU
dc.description.abstract	Journal of Chemistry	ru_RU
dc.description.abstract	Synthesis of β-hydroxysulfides of 1,3-dioxepane series and their further functionalization were performed. Chiral β-hydroxysulfides were separated into enantiomers using enzymatic acylation by lipase PS. Study of antifungal activity of the obtained compounds showed that some enantiomerically pure 6-arylthio-1,3-dioxepan-5-ols represent promising antifungal drug candidates.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	β-Hydroxysulfides	ru_RU
dc.subject	organic synthesis	ru_RU
dc.subject	antifungal activity	ru_RU
dc.title	Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU