| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2019 |
|
Ахметзянова Эльвира Руслановна, автор
Клетенков Константин Сергеевич, автор
Мухамедшина Яна Олеговна, автор
Ризванов Альберт Анатольевич, автор
|
|
Ахметзянова Эльвира Руслановна, автор
|
| Библиографическое описание на языке оригинала |
Akhmetzyanova, E.R., Kletenkov, K.S., Mukhamedshina, Y.O. and Rizvanov, A., 2019. Different approaches to modulation of microglia phenotypes after spinal cord injury. Frontiers in Systems Neuroscience, 13, p.37. |
| Аннотация |
Frontiers in system neuroscience |
| Ключевые слова |
microglia, phenotypes, modulation, spinal cord injury, neuroregeneration. |
| Место издания |
Lausanne |
| Название журнала |
Frontiers in system neuroscience
|
| Издательство |
Frontiers |
| URL |
https://doi.org/10.3389/fnsys.2019.00037 |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=210579 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Ахметзянова Эльвира Руслановна |
ru_RU |
| dc.contributor.author |
Клетенков Константин Сергеевич |
ru_RU |
| dc.contributor.author |
Мухамедшина Яна Олеговна |
ru_RU |
| dc.contributor.author |
Ризванов Альберт Анатольевич |
ru_RU |
| dc.contributor.author |
Ахметзянова Эльвира Руслановна |
ru_RU |
| dc.date.accessioned |
2019-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2019-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2019 |
ru_RU |
| dc.identifier.citation |
Akhmetzyanova, E.R., Kletenkov, K.S., Mukhamedshina, Y.O. and Rizvanov, A., 2019. Different approaches to modulation of microglia phenotypes after spinal cord injury. Frontiers in Systems Neuroscience, 13, p.37. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=210579 |
ru_RU |
| dc.description.abstract |
Frontiers in system neuroscience |
ru_RU |
| dc.description.abstract |
Microglial cells, which are highly plastic, immediately respond to any change in the microenvironment by becoming activated and shifting the phenotype toward neurotoxicity or neuroprotection. The polarization of microglia/macrophages after spinal cord injury (SCI) seems to be a dynamic process and can change depending on the microenvironment, stage, course, and severity of the posttraumatic process. Effective methods to modulate microglia toward a neuroprotective phenotype in order to stimulate neuroregeneration are actively sought for. In this context, available approaches that can selectively impact the polarization of microglia/macrophages regulate synthesis of trophic factors and cytokines/chemokines in them, and their phagocytic function and effects on the course and outcome of SCI are discussed in this review. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.publisher |
Frontiers |
ru_RU |
| dc.subject |
microglia |
ru_RU |
| dc.subject |
phenotypes |
ru_RU |
| dc.subject |
modulation |
ru_RU |
| dc.subject |
spinal cord injury |
ru_RU |
| dc.subject |
neuroregeneration. |
ru_RU |
| dc.title |
Different Approaches to Modulation of Microglia Phenotypes After Spinal Cord Injury |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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