| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2020 |
| Язык | английский |
|
Ильинская Ольга Николаевна, автор
Карамова Назира Сунагатовна, автор
|
|
Ibrahim Omer , автор
Orabi Mohamed , автор
Аbdul-Hafeez Essam , автор
|
| Библиографическое описание на языке оригинала |
Abdul-Hafeez E.Y. In vitro cytotoxic activity of certain succulent plants against human colon, breast and liver cancer cell lines/E.Y. Abdul-Hafeez, M.A.A. Orabi, O.H.M. Ibrahim, O.N. Ilinskaya, N.S. Karamova // South African Journal of Botany. - 2020. – V. 131. – P.: 295 – 301. |
| Аннотация |
South African Journal of Botany |
| Ключевые слова |
Agavaceae family, cytotoxicity, MCF-7, HepG-2, Caco-2, steroidal saponins |
| Название журнала |
South African Journal of Botany
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=231228 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Ильинская Ольга Николаевна |
ru_RU |
| dc.contributor.author |
Карамова Назира Сунагатовна |
ru_RU |
| dc.contributor.author |
Ibrahim Omer |
ru_RU |
| dc.contributor.author |
Orabi Mohamed |
ru_RU |
| dc.contributor.author |
Аbdul-Hafeez Essam |
ru_RU |
| dc.date.accessioned |
2020-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2020-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2020 |
ru_RU |
| dc.identifier.citation |
Abdul-Hafeez E.Y. In vitro cytotoxic activity of certain succulent plants against human colon, breast and liver cancer cell lines/E.Y. Abdul-Hafeez, M.A.A. Orabi, O.H.M. Ibrahim, O.N. Ilinskaya, N.S. Karamova // South African Journal of Botany. - 2020. – V. 131. – P.: 295 – 301. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=231228 |
ru_RU |
| dc.description.abstract |
South African Journal of Botany |
ru_RU |
| dc.description.abstract |
Among the plants which are determined to be a promising source of anticarcenogenic agents are members of
Agavaceae family which are common in tropical and subtropical regions such as Egypt. In this study, cytotoxic
activity were assessed for the methanolic extracts and fractions from five members of Agavaceae family:
Sansevieria cylindrica Bojer., Polianthes tuberosa L., Sansevieria trifasciata Prain., Yucca filamentosa L. and
Furcraea watsoniana Hort. against MCF-7 (breast), HepG-2 (hepatoma), and Caco-2 (colon) cancer cell lines
by MTT method. The n-hexane fraction of P. tuberosa leaves extract demonstrated strong cytotoxic potential
against all three cancer cell lines (CC50<20 mg/ml). The ethyl acetate fractions of Y. filamentosa and F. watsoniana
leaves significantly inhibited proliferation of hepatocellular HepG-2 (CC50 = 6.21 mg/ml and
19.07 mg/ml, respectively) and intestinal epithelium Caco-2 carcinoma cells (CC50 = 18.86 mg/ml and
23.25 mg/ml, respectively). Presumably, the cytotoxic activity exhibited by n-hexane fraction of P. tuberosa,
ethyl acetate fractions of Y. filamentosa and F. watsoniana may be related to the steroidal saponins that are
present in these samples. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Agavaceae family |
ru_RU |
| dc.subject |
cytotoxicity |
ru_RU |
| dc.subject |
MCF-7 |
ru_RU |
| dc.subject |
HepG-2 |
ru_RU |
| dc.subject |
Caco-2 |
ru_RU |
| dc.subject |
steroidal saponins |
ru_RU |
| dc.title |
In vitro cytotoxic activity of certain succulent plants against human colon, breast and liver cancer cell lines |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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