| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2020 |
| Язык | английский |
|
Аймалетдинов Александр Маазович, автор
Антропова Александра Владимировна, автор
Закирова Елена Юрьевна, автор
Кабве Эммануэль , автор
Ризванов Альберт Анатольевич, автор
|
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Catrin Rutland , автор
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| Библиографическое описание на языке оригинала |
Aimaletdinov, A., Mindubaeva, G., Khalikova, S., Kabwe, E., Salmakova, A., Alexandrova, N., Rutland, C., Rizvanov, A. and Zakirova, E. 2020. Application of gene therapy in the treatment of superficial digital flexor tendon injury in horses. Open Vet. J. 10(3), 261-266. |
| Аннотация |
open veterinary journal |
| Ключевые слова |
Keywords: Fibroblast growth factor 2, Plasmid DNA, Superficial digital flexor, Vascular endothelial growth factor. |
| Название журнала |
open veterinary journal
|
| URL |
https://www.openveterinaryjournal.com/aimaletdinov-abst-ovj-048 |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=237062 |
| Файлы ресурса | |
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Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Аймалетдинов Александр Маазович |
ru_RU |
| dc.contributor.author |
Антропова Александра Владимировна |
ru_RU |
| dc.contributor.author |
Закирова Елена Юрьевна |
ru_RU |
| dc.contributor.author |
Кабве Эммануэль |
ru_RU |
| dc.contributor.author |
Ризванов Альберт Анатольевич |
ru_RU |
| dc.contributor.author |
Catrin Rutland |
ru_RU |
| dc.date.accessioned |
2020-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2020-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2020 |
ru_RU |
| dc.identifier.citation |
Aimaletdinov, A., Mindubaeva, G., Khalikova, S., Kabwe, E., Salmakova, A., Alexandrova, N., Rutland, C., Rizvanov, A. and Zakirova, E. 2020. Application of gene therapy in the treatment of superficial digital flexor tendon injury in horses. Open Vet. J. 10(3), 261-266. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=237062 |
ru_RU |
| dc.description.abstract |
open veterinary journal |
ru_RU |
| dc.description.abstract |
Background: Tendon injuries are one of the most common causes of orthopedic disorders in horses. Such injuries involve a long course of treatment and recovery. The most promising method of treating these injuries is the use of recombinant proteins and gene therapy.
Aim: In this work, we evaluated the therapeutic efficacy of plasmid DNA containing two species-specific coding sequences of vascular endothelial growth factor 164 and fibroblast growth factor 2 in the treatment of severe damage to the tendon of the superficial digital flexor.
Methods: A plasmid DNA construct was used to restore the damaged superficial digital flexor tendon in the horse.
Results: The study showed that administration of plasmid DNA encoding vascular endothelial growth factor 164 and fibroblast growth factor 2 genes at the injury area increased the regenerative activities of the damaged tendon.
Conclusion: This study shows the therapeutic properties of genetic constructs (pDNA) and contributes to the advancements in the use of these therapies. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Keywords: Fibroblast growth factor 2 |
ru_RU |
| dc.subject |
Plasmid DNA |
ru_RU |
| dc.subject |
Superficial digital flexor |
ru_RU |
| dc.subject |
Vascular endothelial growth factor. |
ru_RU |
| dc.title |
Application of gene therapy in the treatment of superficial digital flexor tendon injury in horses |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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