КФУ. Карточка публикации. Spectroscopic and in vitro investigations of boron(III) complex with meso-4-methoxycarbonylpropylsubstituted dipyrromethene for fluorescence bioimaging applications

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SPECTROSCOPIC AND IN VITRO INVESTIGATIONS OF BORON(III) COMPLEX WITH MESO-4-METHOXYCARBONYLPROPYLSUBSTITUTED DIPYRROMETHENE FOR FLUORESCENCE BIOIMAGING APPLICATIONS

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2020

Язык

английский

Авторы, сотрудники КФУ

Исламов Даут Ринатович, автор

Каюмов Айрат Рашитович, автор

Павельев Роман Сергеевич, автор

Усачев Константин Сергеевич, автор

Библиографическое описание на языке оригинала

Guseva G, Antina E, Berezin M, Spectroscopic and in vitro investigations of boron(III) complex with meso-4-methoxycarbonylpropylsubstituted dipyrromethene for fluorescence bioimaging applications//Molecules. - 2020. - Vol.25, Is.19. - Art. № 4541.

Аннотация

This study focuses on the behavior of a new fluorescent marker for labeling individual biomolecules and staining cell organelles developed on a meso-substituted BODIPY platform. Boron(III) complex with meso-4-methoxycarbonylpropylsubstituted 3,3',5,5'-tetramethyl-2,2'-dipyrromethene has been synthesized and identified via visible, UV-, NMR- and MS-spectra X-ray. The behavior of fluorophore in solutions has been studied with various experimental techniques. It has been found that luminophore exhibits a high quantum yield (almost ~100–75%) in the blue-green region (513–520 nm) and has high photostability. In addition, biological analysis indicates that the fluorophore exhibits a tendency to effectively penetrate into cell membranes. On the other hand, the proposed BODIPY can be used to study the significant differences among a large number of pathogens of mycotic infections, as well as to visualize structural changes in the plasma membrane, which is necessary for the clearance of mammalian cells undergoing apoptotic cell death.

Ключевые слова

dipyrromethene, BODIPY, fluorophore, biomarker, pathogenic microorganisms

Название журнала

Molecules

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85092559267&doi=10.3390%2fmolecules25194541&partnerID=40&md5=dda95582ac829e12cde07febd7711669

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https://repository.kpfu.ru/?p_id=240250

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Исламов Даут Ринатович	ru_RU
dc.contributor.author	Каюмов Айрат Рашитович	ru_RU
dc.contributor.author	Павельев Роман Сергеевич	ru_RU
dc.contributor.author	Усачев Константин Сергеевич	ru_RU
dc.date.accessioned	2020-01-01T00:00:00Z	ru_RU
dc.date.available	2020-01-01T00:00:00Z	ru_RU
dc.date.issued	2020	ru_RU
dc.identifier.citation	Guseva G, Antina E, Berezin M, Spectroscopic and in vitro investigations of boron(III) complex with meso-4-methoxycarbonylpropylsubstituted dipyrromethene for fluorescence bioimaging applications//Molecules. - 2020. - Vol.25, Is.19. - Art. № 4541.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=240250	ru_RU
dc.description.abstract	Molecules	ru_RU
dc.description.abstract	This study focuses on the behavior of a new fluorescent marker for labeling individual biomolecules and staining cell organelles developed on a meso-substituted BODIPY platform. Boron(III) complex with meso-4-methoxycarbonylpropylsubstituted 3,3',5,5'-tetramethyl-2,2'-dipyrromethene has been synthesized and identified via visible, UV-, NMR- and MS-spectra X-ray. The behavior of fluorophore in solutions has been studied with various experimental techniques. It has been found that luminophore exhibits a high quantum yield (almost ~100–75%) in the blue-green region (513–520 nm) and has high photostability. In addition, biological analysis indicates that the fluorophore exhibits a tendency to effectively penetrate into cell membranes. On the other hand, the proposed BODIPY can be used to study the significant differences among a large number of pathogens of mycotic infections, as well as to visualize structural changes in the plasma membrane, which is necessary for the clearance of mammalian cells undergoing apoptotic cell death.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	dipyrromethene	ru_RU
dc.subject	BODIPY	ru_RU
dc.subject	fluorophore	ru_RU
dc.subject	biomarker	ru_RU
dc.subject	pathogenic microorganisms	ru_RU
dc.title	Spectroscopic and in vitro investigations of boron(III) complex with meso-4-methoxycarbonylpropylsubstituted dipyrromethene for fluorescence bioimaging applications	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU