КФУ. Карточка публикации. Synthetic route optimization of pyridosept antiseptic drug candidate

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SYNTHETIC ROUTE OPTIMIZATION OF PYRIDOSEPT ANTISEPTIC DRUG CANDIDATE

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2021

Язык

английский

Авторы, сотрудники КФУ

Павельев Роман Сергеевич, автор

Библиографическое описание на языке оригинала

Sapozhnikov S.V, Pavelyev R.S, Shtyrlin N.V, Synthetic route optimization of pyridosept antiseptic drug candidate//AIP Conference Proceedings. - 2021. - Vol.2388, Is.. - Art. №030040.

Аннотация

In this work we have described the transformation of synthetic route of the antiseptic drug candidate Pyridosept. Initial method has included in seven steps and has poor overall yield of target compound. This is the convenient developing process, scalable and technologi. The overall yield was increased up to 22% in four steps without column chromatography purification which allows to obtain the target compound with purity of 99.5+% which is especially important for the active ingredient.

Ключевые слова

pyridoxine, vitamin B6, antiseptic

Название журнала

AIP Conference Proceedings

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120410305&doi=10.1063%2f5.0068420&partnerID=40&md5=d35907ab35f3080ef4a200cb123f35d2

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https://repository.kpfu.ru/?p_id=261926

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Павельев Роман Сергеевич	ru_RU
dc.date.accessioned	2021-01-01T00:00:00Z	ru_RU
dc.date.available	2021-01-01T00:00:00Z	ru_RU
dc.date.issued	2021	ru_RU
dc.identifier.citation	Sapozhnikov S.V, Pavelyev R.S, Shtyrlin N.V, Synthetic route optimization of pyridosept antiseptic drug candidate//AIP Conference Proceedings. - 2021. - Vol.2388, Is.. - Art. №030040.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=261926	ru_RU
dc.description.abstract	AIP Conference Proceedings	ru_RU
dc.description.abstract	In this work we have described the transformation of synthetic route of the antiseptic drug candidate Pyridosept. Initial method has included in seven steps and has poor overall yield of target compound. This is the convenient developing process, scalable and technologi. The overall yield was increased up to 22% in four steps without column chromatography purification which allows to obtain the target compound with purity of 99.5+% which is especially important for the active ingredient.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	pyridoxine	ru_RU
dc.subject	vitamin B6	ru_RU
dc.subject	antiseptic	ru_RU
dc.title	Synthetic route optimization of pyridosept antiseptic drug candidate	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU