| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2023 |
| Язык | русский |
|
Зефиров Тимур Львович, автор
Зиятдинова Нафиса Ильгизовна, автор
Купцова Анна Михайловна, автор
Фасхутдинов Ленар Ильсурович, автор
|
|
Вахитов Линар Илдарович, автор
|
| Библиографическое описание на языке оригинала |
Kuptsova A.M. Rat cardiomyocytes electrical activity during
α2-adrenoreceptors stimulation after If currents blockade /A.M. Kuptsova, L.I. Faskhutdinov, L.I Vakhitov, N.I. Ziyatdinova, T.L. Zefirov // Biophysical Reviews. - 2023. - Vol. 15. - p. 1468-1469. |
| Аннотация |
Biophysical Reviews |
| Ключевые слова |
α2-adrenoreceptors, If currents, rat heart |
| Название журнала |
Biophysical Reviews
|
| URL |
https://link.springer.com/article/10.1007/s12551-023-01150-w |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=290489 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Зефиров Тимур Львович |
ru_RU |
| dc.contributor.author |
Зиятдинова Нафиса Ильгизовна |
ru_RU |
| dc.contributor.author |
Купцова Анна Михайловна |
ru_RU |
| dc.contributor.author |
Фасхутдинов Ленар Ильсурович |
ru_RU |
| dc.contributor.author |
Вахитов Линар Илдарович |
ru_RU |
| dc.date.accessioned |
2023-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2023-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2023 |
ru_RU |
| dc.identifier.citation |
Kuptsova A.M. Rat cardiomyocytes electrical activity during
α2-adrenoreceptors stimulation after If currents blockade /A.M. Kuptsova, L.I. Faskhutdinov, L.I Vakhitov, N.I. Ziyatdinova, T.L. Zefirov // Biophysical Reviews. - 2023. - Vol. 15. - p. 1468-1469. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=290489 |
ru_RU |
| dc.description.abstract |
Biophysical Reviews |
ru_RU |
| dc.description.abstract |
The α2-adrenoreceptors (α2-AR) in mammalian heart perform the
functions of regulatory efects modulation. Activation of α2-AR inhib
its the synthesis of cyclic adenosine monophosphate (cAMP) by ade
nylate cyclase. If currents of the myocardium cells are modulated by
the level of cAMP, sympathetic and parasympathetic departments of
the autonomic nervous system. Modulation of the If currents activity
via cAMP is essential in the increase or decrease of heart rate by the
departments of the autonomic nervous system. It has been shown that
activation of adrenergic receptors activates If and thereby increases the
chronotropic function of the heart through β-adrenoreceptor dependent
increase in the level of cAMP. Since HCN channels and α2-AR are pre
sent in cardiomyocytes, it is possible that If currents are an efector of
adrenergic regulation of the heart through this type of receptor as well.
The aim of this study is to investigate the efect of α2-adrenoreceptor
stimulation after If preliminary blockade on the electrical activity of
rat cardiomyocytes. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
α2-adrenoreceptors |
ru_RU |
| dc.subject |
If currents |
ru_RU |
| dc.subject |
rat heart |
ru_RU |
| dc.title |
Rat cardiomyocytes electrical activity during
α2-adrenoreceptors stimulation after If currents blockade |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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