| Форма представления | Статьи в российских журналах и сборниках |
| Год публикации | 2025 |
| Язык | русский |
|
Зефиров Тимур Львович, автор
Зиятдинова Нафиса Ильгизовна, автор
Искаков Никита Георгиевич, автор
Купцова Анна Михайловна, автор
Мансур Нур , автор
|
|
Зверев Алексей Анатольевич, автор
|
| Библиографическое описание на языке оригинала |
Kuptsova A.M. RIGHT ATRIAL CARDIOMYOCYTES ACTION POTENTIAL AMPLITUDE-TIME CHARACTERISTICS UNDER LEFT VENTRICLE EXPERIMENTAL MYOCARDIAL INFARCTION / A.M.Kuptsova, N. Mansour, A.A. Zverev, N.G. Iskakov, N.I. Ziyatdinova, T.L. Zefirov // Opera Med Physiol. 2025. - Vol. 12 (2). - р. 68-73. |
| Аннотация |
Cardiovascular diseases are among the most prevalent pathologies worldwide, and myocardial infarction (MI) is a common cause of ventricular arrhythmias and sudden cardiac death. The development of MI is accompanied by profound alterations in the electrophysiological properties of cardiomyocytes, including a decrease in the amplitude and propagation velocity of the action potential. These changes lead to disturbances in excitability and impulse conduction not only in the affected region but also throughout the entire heart. Understanding the mechanisms underlying these alterations is crucial for developing novel approaches to the prevention and treatment of cardiovascular complications. The study aimed to investigate the dynamics of electrical activity changes in the right atrial myocardium at different stages of left ventricular myocardial infarction (MI) development in rats. Experimental MI was induced by ligation of the left coronary artery. We evaluated the effects of acute, subacute, and long-term consequences MI phases on the amplitude-time characteristics of action potentials in working right atrial cardiomyocytes. |
| Ключевые слова |
myocardial infarction, action potential duration, heart, rat. |
| Название журнала |
Opera Medica et Physiologica
|
| URL |
https://operamedphys.org/content/right-atrial-cardiomyocytes-action-potential-amplitude-time-characteristics-under-left-0 |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=314837 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Зефиров Тимур Львович |
ru_RU |
| dc.contributor.author |
Зиятдинова Нафиса Ильгизовна |
ru_RU |
| dc.contributor.author |
Искаков Никита Георгиевич |
ru_RU |
| dc.contributor.author |
Купцова Анна Михайловна |
ru_RU |
| dc.contributor.author |
Мансур Нур |
ru_RU |
| dc.contributor.author |
Зверев Алексей Анатольевич |
ru_RU |
| dc.date.accessioned |
2025-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2025-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2025 |
ru_RU |
| dc.identifier.citation |
Kuptsova A.M. RIGHT ATRIAL CARDIOMYOCYTES ACTION POTENTIAL AMPLITUDE-TIME CHARACTERISTICS UNDER LEFT VENTRICLE EXPERIMENTAL MYOCARDIAL INFARCTION / A.M.Kuptsova, N. Mansour, A.A. Zverev, N.G. Iskakov, N.I. Ziyatdinova, T.L. Zefirov // Opera Med Physiol. 2025. - Vol. 12 (2). - р. 68-73. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=314837 |
ru_RU |
| dc.description.abstract |
Opera Medica et Physiologica |
ru_RU |
| dc.description.abstract |
Cardiovascular diseases are among the most prevalent pathologies worldwide, and myocardial infarction (MI) is a common cause of ventricular arrhythmias and sudden cardiac death. The development of MI is accompanied by profound alterations in the electrophysiological properties of cardiomyocytes, including a decrease in the amplitude and propagation velocity of the action potential. These changes lead to disturbances in excitability and impulse conduction not only in the affected region but also throughout the entire heart. Understanding the mechanisms underlying these alterations is crucial for developing novel approaches to the prevention and treatment of cardiovascular complications. The study aimed to investigate the dynamics of electrical activity changes in the right atrial myocardium at different stages of left ventricular myocardial infarction (MI) development in rats. Experimental MI was induced by ligation of the left coronary artery. We evaluated the effects of acute, subacute, and long-term consequences MI phases on the amplitude-time characteristics of action potentials in working right atrial cardiomyocytes. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
myocardial infarction |
ru_RU |
| dc.subject |
action potential duration |
ru_RU |
| dc.subject |
heart |
ru_RU |
| dc.subject |
rat. |
ru_RU |
| dc.title |
RIGHT ATRIAL CARDIOMYOCYTES ACTION POTENTIAL AMPLITUDE-TIME CHARACTERISTICS UNDER LEFT VENTRICLE EXPERIMENTAL MYOCARDIAL INFARCTION |
ru_RU |
| dc.type |
Статьи в российских журналах и сборниках |
ru_RU |
|
EN 
中文 
ES 
Карта сайта
