КФУ. Карточка публикации. A voltammetric sensor based on tin dioxide nanoparticles for the determination of Taxifolin

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A VOLTAMMETRIC SENSOR BASED ON TIN DIOXIDE NANOPARTICLES FOR THE DETERMINATION OF TAXIFOLIN

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2025

Язык

английский

Авторы, сотрудники КФУ

Зиятдинова Гузель Камилевна, автор

Авторы, студенты КФУ

Тарабукина Анна Денисовна, автор

Библиографическое описание на языке оригинала

Ziyatdinova, G.K. A voltammetric sensor based on tin dioxide nanoparticles for the determination of Taxifolin / G.K. Ziyatdinova, A.D. Tarabukina // J. Anal. Chem. - 2025. - V. 80. - № 7. - P. 1264-1273.

Аннотация

A voltammetric sensor for the determination of taxifolin is developed based on a glassy carbon electrode (GCE) modified with tin dioxide nanoparticles (SnO2 NPs) dispersed in N-hexadecylpyridinium bromide. The modification of the electrode surface enhances the reversibility of the electrochemical reaction and significantly increases redox currents compared to an unmodified GCE, by factors of 2.3 and 3.3 for the anodic and cathodic peaks, respectively. Scanning electron microscopy reveals a uniformly distributed layer of spherical SnO2 NPs on the electrode surface; their diameters range from 20 to 40 nm. This modification results in a 3.9-fold increase in the electrode's effective surface area and a 143-fold enhancement in the heterogeneous electron transfer rate constant. It was found that the electrooxidation of taxifolin involves protons. The electrode reaction follows a mixed control mechanism including both diffusion and adsorption components. Under differential pulse voltammetry conditions, using Britton–Robinson buffer of pH 6.0, the sensor detects taxifolin over a concentration range of 0.075 to 25 μM, with a limit of detection of 70.7 nM. These analytical parameters are comparable to those achieved by other electrochemical techniques; however, the proposed method offers greater simplicity and higher speed, and does not require complex electrode modification. The sensor demonstrated successful application to the analysis of dietary supplements containing dihydroquercetin (taxifolin). The results aligned with those obtained by coulometric titration using electrochemically generated bromine.

Ключевые слова

Electrochemical sensors, modified electrodes, voltammetry, phenolic antioxidants, pharmaceutical analysis

Название журнала

JOURNAL OF ANALYTICAL CHEMISTRY

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-105011693757&doi=10.1134%2fS1061934825700558&partnerID=40&md5=fe00cffea9248a2a2828926500c7cc53

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https://repository.kpfu.ru/?p_id=316808

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Зиятдинова Гузель Камилевна	ru_RU
dc.contributor.author	Тарабукина Анна Денисовна	ru_RU
dc.date.accessioned	2025-01-01T00:00:00Z	ru_RU
dc.date.available	2025-01-01T00:00:00Z	ru_RU
dc.date.issued	2025	ru_RU
dc.identifier.citation	Ziyatdinova, G.K. A voltammetric sensor based on tin dioxide nanoparticles for the determination of Taxifolin / G.K. Ziyatdinova, A.D. Tarabukina // J. Anal. Chem. - 2025. - V. 80. - № 7. - P. 1264-1273.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=316808	ru_RU
dc.description.abstract	JOURNAL OF ANALYTICAL CHEMISTRY	ru_RU
dc.description.abstract	A voltammetric sensor for the determination of taxifolin is developed based on a glassy carbon electrode (GCE) modified with tin dioxide nanoparticles (SnO2 NPs) dispersed in N-hexadecylpyridinium bromide. The modification of the electrode surface enhances the reversibility of the electrochemical reaction and significantly increases redox currents compared to an unmodified GCE, by factors of 2.3 and 3.3 for the anodic and cathodic peaks, respectively. Scanning electron microscopy reveals a uniformly distributed layer of spherical SnO2 NPs on the electrode surface; their diameters range from 20 to 40 nm. This modification results in a 3.9-fold increase in the electrode's effective surface area and a 143-fold enhancement in the heterogeneous electron transfer rate constant. It was found that the electrooxidation of taxifolin involves protons. The electrode reaction follows a mixed control mechanism including both diffusion and adsorption components. Under differential pulse voltammetry conditions, using Britton–Robinson buffer of pH 6.0, the sensor detects taxifolin over a concentration range of 0.075 to 25 μM, with a limit of detection of 70.7 nM. These analytical parameters are comparable to those achieved by other electrochemical techniques; however, the proposed method offers greater simplicity and higher speed, and does not require complex electrode modification. The sensor demonstrated successful application to the analysis of dietary supplements containing dihydroquercetin (taxifolin). The results aligned with those obtained by coulometric titration using electrochemically generated bromine.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Electrochemical sensors	ru_RU
dc.subject	modified electrodes	ru_RU
dc.subject	voltammetry	ru_RU
dc.subject	phenolic antioxidants	ru_RU
dc.subject	pharmaceutical analysis	ru_RU
dc.title	A voltammetric sensor based on tin dioxide nanoparticles for the determination of Taxifolin	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU