| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2013 |
| Язык | английский |
|
Мунавиров Булат Василевич, автор
Рудакова Майя Анатольевна, автор
Филиппов Андрей Васильевич, автор
|
| Библиографическое описание на языке оригинала |
B.Munavirov, O.Gnezdilov, M.Rudakova, O.Antzutkin, A.Filippov Interaction of polyacrylic acid with lipid bilayers: Effect of polymer mass. // Magnetic Resonance in Chemistry. 2013. V. 51. P.750-755. |
| Аннотация |
MAGN RESON CHEM |
| Ключевые слова |
Interaction, polyacrylic acid, lipid bilayers, polymer mass, NMR |
| Название журнала |
MAGN RESON CHEM
|
| URL |
http://onlinelibrary.wiley.com/doi/10.1002/mrc.4013/full |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=68278 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Мунавиров Булат Василевич |
ru_RU |
| dc.contributor.author |
Рудакова Майя Анатольевна |
ru_RU |
| dc.contributor.author |
Филиппов Андрей Васильевич |
ru_RU |
| dc.date.accessioned |
2013-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2013-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2013 |
ru_RU |
| dc.identifier.citation |
B.Munavirov, O.Gnezdilov, M.Rudakova, O.Antzutkin, A.Filippov Interaction of polyacrylic acid with lipid bilayers: Effect of polymer mass. // Magnetic Resonance in Chemistry. 2013. V. 51. P.750-755. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=68278 |
ru_RU |
| dc.description.abstract |
MAGN RESON CHEM |
ru_RU |
| dc.description.abstract |
MAGN RESON CHEM |
ru_RU |
| dc.description.abstract |
Polyanion-coated lipid vesicles are proposed to have an appreciable potential for drug delivery because of their ability to control
the permeability of lipid bilayers by environmental parameters such as pH and temperature. However, details of the interaction of
this class of polymers with lipids and theirmechanisms of induced permeability are still being debated. In thiswork,we applied 1H
NOESY to study details of the interaction of polyacrylic acid (PAA) fractions of molecular weights 5 and 240 kDa with
dimyristoylphosphatidylcholine vesicles.We showed that PAA of two differentmolecularmassesmodifies lipid bilayers increasing
disorder and probability of close contact between polar and hydrophobic groups. PAA molecules adsorb near the interface of lipid
bilayers but do not penetrate into the hydrophobic core of the bilayer and, thus, cannot participate in formation of transbilayer
channels, proposed in earlier works. Increasing the molecular mass of PAA from 5 kDa to 240kDa does not ch |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Interaction |
ru_RU |
| dc.subject |
polyacrylic acid |
ru_RU |
| dc.subject |
lipid bilayers |
ru_RU |
| dc.subject |
polymer mass |
ru_RU |
| dc.subject |
NMR |
ru_RU |
| dc.title |
Interaction of polyacrylic acid with lipid bilayers: Effect of polymer mass |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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