| Форма представления | Статьи в российских журналах и сборниках |
| Год публикации | 2014 |
|
Зарипова Раиля Ирековна, автор
Зефиров Тимур Львович, автор
|
| Библиографическое описание на языке оригинала |
Effect of NO Synthase Blockade on NO Production
in Rat Heart under Conditions of Hypokinesia |
| Аннотация |
Electron paramagnetic (EPR) spectroscopy study showed that 90-day hypokinesia in rats is
accompanied by an increase in NO production in the heart. A nonselective NO synthase inhibitor
L-NAME decreased the content of NO in the heart atria and ventricles of hypokinetic rats
by 67-70%. A selective inhibitor of inducible NO synthase, aminoguanidine, also decreased
the level of NO in the heart atria and ventricles of hypokinetic rats by 60-65%. Our results
indicate that the increase in NO production during hypokinesia is associated with activation
of NO synthases. |
| Ключевые слова |
NO; heart; rat; hypokinesia; electron paramagnetic resonance |
| Название журнала |
Bulletin of Experimental Biology and Medicine
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=92001 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Зарипова Раиля Ирековна |
ru_RU |
| dc.contributor.author |
Зефиров Тимур Львович |
ru_RU |
| dc.date.accessioned |
2014-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2014-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2014 |
ru_RU |
| dc.identifier.citation |
Effect of NO Synthase Blockade on NO Production
in Rat Heart under Conditions of Hypokinesia |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=92001 |
ru_RU |
| dc.description.abstract |
Bulletin of Experimental Biology and Medicine |
ru_RU |
| dc.description.abstract |
Electron paramagnetic (EPR) spectroscopy study showed that 90-day hypokinesia in rats is
accompanied by an increase in NO production in the heart. A nonselective NO synthase inhibitor
L-NAME decreased the content of NO in the heart atria and ventricles of hypokinetic rats
by 67-70%. A selective inhibitor of inducible NO synthase, aminoguanidine, also decreased
the level of NO in the heart atria and ventricles of hypokinetic rats by 60-65%. Our results
indicate that the increase in NO production during hypokinesia is associated with activation
of NO synthases. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
|
ru_RU |
| dc.title |
Effect of NO Synthase Blockade on NO Production
in Rat Heart under Conditions of Hypokinesia |
ru_RU |
| dc.type |
Статьи в российских журналах и сборниках |
ru_RU |
|
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