KFU. Card publication. «Doubly enantiophobic» behavior during crystallization of racemic 1,5-dihydro-2H-pyrrol-2-one thioether

KAZAN
FEDERAL UNIVERSITY

- RUS
- 中文
- ES

&LAQUO;DOUBLY ENANTIOPHOBIC&RAQUO; BEHAVIOR DURING CRYSTALLIZATION OF RACEMIC 1,5-DIHYDRO-2H-PYRROL-2-ONE THIOETHER

Form of presentation

Articles in international journals and collections

Year of publication

2018

��

��

Authors, employees of KFU

Kurbangalieva Almira Rafaelovna, author

Lodochnikova Olga Aleksandrovna, author

Potapova Lyubov Nikolaevna, author

Authors, students KFU

Zaripova Aygul Ramilevna, author

Bibliographic description in the original language

Lodochnikova O. A. «Doubly enantiophobic» behavior during crystallization of racemic 1,5-dihydro-2H-pyrrol-2-one thioether / O. A. Lodochnikova, A. R. Zaripova, R. R. Fayzullin, A. I. Samigullina, I. I. Vandyukova, L. N. Potapova, A. R. Kurbangalieva // CrystEngComm. – 2018. – V. 20, � 23. – P. 3218–3227.

Annotation

The titled compound 7 demonstrates unusual «doubly enantiophobic« behavior during crystallization. Namely, the mentioned substance forms two polymorphic modifications 7a and 7b that appear to be racemic conglomerates in the space groups P21 and P65 (or P61), respectively. Both 7a and 7b are thermodynamically stable at certain temperature ranges. Hence, γ-lactam 7 is prone to spontaneous resolution of the racemate into the enantiomers in two different ways, which is an exceptional phenomenon. Phase behavior and structure of the crystalline modifications of 7 were investigated by means of single crystal and powder X-ray diffraction, differential scanning calorimetry, temperature-resolved vibration spectroscopy, and hot-stage microscopy.

Keywords

3-Pyrrolin-2-one, conglomerate, spontaneous resolution

The name of the journal

CRYSTENGCOMM

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048447909&doi=10.1039%2fc8ce00369f&partnerID=40&md5=8debfa970609aaed4f16fe3ae0f61034

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=183293&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kurbangalieva Almira Rafaelovna	ru_RU
dc.contributor.author	Lodochnikova Olga Aleksandrovna	ru_RU
dc.contributor.author	Potapova Lyubov Nikolaevna	ru_RU
dc.contributor.author	Zaripova Aygul Ramilevna	ru_RU
dc.date.accessioned	2018-01-01T00:00:00Z	ru_RU
dc.date.available	2018-01-01T00:00:00Z	ru_RU
dc.date.issued	2018	ru_RU
dc.identifier.citation	Lodochnikova �. �. «Doubly enantiophobic» behavior during crystallization of racemic 1,5-dihydro-2H-pyrrol-2-one thioether / O. A. Lodochnikova, A. R. Zaripova, R. R. Fayzullin, A. I. Samigullina, I. I. Vandyukova, L. N. Potapova, A. R. Kurbangalieva // CrystEngComm. – 2018. – V. 20, � 23. – P. 3218–3227.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=183293&p_lang=2	ru_RU
dc.description.abstract	CRYSTENGCOMM	ru_RU
dc.description.abstract	The titled compound 7 demonstrates unusual «doubly enantiophobic« behavior during crystallization. Namely, the mentioned substance forms two polymorphic modifications 7a and 7b that appear to be racemic conglomerates in the space groups P21 and P65 (or P61), respectively. Both 7a and 7b are thermodynamically stable at certain temperature ranges. Hence, γ-lactam 7 is prone to spontaneous resolution of the racemate into the enantiomers in two different ways, which is an exceptional phenomenon. Phase behavior and structure of the crystalline modifications of 7 were investigated by means of single crystal and powder X-ray diffraction, differential scanning calorimetry, temperature-resolved vibration spectroscopy, and hot-stage microscopy.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	3-Pyrrolin-2-one	ru_RU
dc.subject	conglomerate	ru_RU
dc.subject	spontaneous resolution	ru_RU
dc.title	«Doubly enantiophobic» behavior during crystallization of racemic 1,5-dihydro-2H-pyrrol-2-one thioether	ru_RU
dc.type	Articles in international journals and collections	ru_RU