KFU. Card publication. (Gd3+) Complexation with oligopeptide (SFVG) and amyloid peptide (Aβ13–23) in aqueous solution by NMR spectroscopy

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(GD3+) COMPLEXATION WITH OLIGOPEPTIDE (SFVG) AND AMYLOID PEPTIDE (Aβ13&NDASH;23) IN AQUEOUS SOLUTION BY NMR SPECTROSCOPY

Form of presentation

Articles in international journals and collections

Year of publication

2023

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Authors, employees of KFU

Blokhin Dmitriy Sergeevich, author

Ilyasov Kamil Akhatovich, author

Klochkov Aleksandr Vladimirovich, author

Klochkov Vladimir Vasilevich, author

Rakhmatullin Ilfat Zufarovich, author

Tarasov Artem Sergeevich, author

Authors, postgraduates KFU

Tarasov Artem Sergeevich, postgraduate kfu

Bibliographic description in the original language

Tarasov A.S., et al. (Gd3+) Complexation with oligopeptide (SFVG) and amyloid peptide (Aβ13–23) in aqueous solution by NMR spectroscopy / A.S. Tarasov, I.Z. Rakhmatullin, D.S. Blokhin, A.V. Klochkov, K.A. Il'yasov, V.V. Klochkov // Results in Chemistry. - 2023. - Vol. 5. - � 100762. Pp. - 7. https://doi.org/10.1016/j.rechem.2023.100762.

Annotation

Results in Chemistry

Keywords

NMR spectroscopy, Amyloid peptide (Aβ13-23), tetrapeptide (SFVG), Gadolinium (III) chloride

The name of the journal

Results in Chemistry

URL

https://doi.org/10.1016/j.rechem.2023.100762

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=275124&p_lang=2

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Full metadata record

Field DC	Value	Language
dc.contributor.author	Blokhin Dmitriy Sergeevich	ru_RU
dc.contributor.author	Ilyasov Kamil Akhatovich	ru_RU
dc.contributor.author	Klochkov Aleksandr Vladimirovich	ru_RU
dc.contributor.author	Klochkov Vladimir Vasilevich	ru_RU
dc.contributor.author	Rakhmatullin Ilfat Zufarovich	ru_RU
dc.contributor.author	Tarasov Artem Sergeevich	ru_RU
dc.contributor.author	Tarasov Artem Sergeevich	ru_RU
dc.date.accessioned	2023-01-01T00:00:00Z	ru_RU
dc.date.available	2023-01-01T00:00:00Z	ru_RU
dc.date.issued	2023	ru_RU
dc.identifier.citation	Tarasov A.S., et al. (Gd3+) Complexation with oligopeptide (SFVG) and amyloid peptide (Aβ13–23) in aqueous solution by NMR spectroscopy / A.S. Tarasov, I.Z. Rakhmatullin, D.S. Blokhin, A.V. Klochkov, K.A. Il'yasov, V.V. Klochkov // Results in Chemistry. - 2023. - Vol. 5. - � 100762. Pp. - 7. https://doi.org/10.1016/j.rechem.2023.100762.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=275124&p_lang=2	ru_RU
dc.description.abstract	Results in Chemistry	ru_RU
dc.description.abstract	Gadolinium (III) ion, which belongs to the subgroup of transition metal ions, has practical importance for magnetic resonance imaging (MRI) with contrast. The accumulation of complexes of transition metal ions with amyloid peptides in the human body leads to the formation of insoluble plaques, which are presumably-one of the causes of Alzheimer's disease. This paper presents the results of studying the interaction of the gadolinium (III) ion with a fragment of amyloid protein Aβ40 in aqueous solutions using nuclear magnetic resonance spectroscopy. Tetrapeptide (SFVG) was used as the simplified model of metal-peptide interaction research. Beta-amyloid peptide (Aβ13-23) was chosen as the amyloid protein Aβ40 fragment model. Analysis of 1H NMR spectra revealed that the interaction exists for both types of molecules. It was also suggested the possible location of gadolinium (III) ion in the studied molecules.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	NMR spectroscopy	ru_RU
dc.subject	Amyloid peptide (Aβ13-23)	ru_RU
dc.subject	tetrapeptide (SFVG)	ru_RU
dc.subject	Gadolinium (III) chloride	ru_RU
dc.title	(Gd3+) Complexation with oligopeptide (SFVG) and amyloid peptide (Aβ13–23) in aqueous solution by NMR spectroscopy	ru_RU
dc.type	Articles in international journals and collections	ru_RU