| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2016 |
| Язык | английский |
|
Журавлева Маргарита Николаевна, автор
Киясов Андрей Павлович, автор
Масгутов Руслан Фаридович, автор
Масгутова Галина Андреевна, автор
Мухамедшина Яна Олеговна, автор
Мухаметшина Регина Рустамовна, автор
Ризванов Альберт Анатольевич, автор
Салафутдинов Ильнур Ильдусович, автор
|
|
Lima LM, Reis HJ, Palotás A Lima LM, Reis HJ, Palotás A , автор
|
| Библиографическое описание на языке оригинала |
Masgutov RF Human adipose-derived stem cells stimulate neuroregeneration. Masgutov RF, Masgutova GA, Zhuravleva MN, Salafutdinov II, Mukhametshina RT, Mukhamedshina YO, Lima LM, Reis HJ, Kiyasov AP, Palotás A, Rizvanov AA.// Clin Exp Med. 2016 Aug;16(3):451-61. doi: 10.1007/s10238-015-0364-3. Epub 2015 Jun 6. |
| Аннотация |
Traumatic brain injuries and degenerative neurological disorders such as Alzheimer's dementia, Parkinson's disease, amyotrophic lateral sclerosis and many others are characterized by loss of brain cells and supporting structures. Restoring microanatomy and function using stem cells is a promising therapeutic approach. Among the many various sources, adipose-derived stem cells (ADSCs) are one of the most easily harvested alternatives, they multiply rapidly, and they demonstrate low immunogenicity with an ability to differentiate into several cell types. The objective of this study was to evaluate the effect of xenotransplanted human ADSCs on post-traumatic regeneration of rat sciatic nerve. Peripheral reconstruction following complete sciatic transection and autonerve grafting was complemented by intra-operative injection of hADSCs into the proximal and distal stumps. The injury caused gliosis and apoptosis of sensory neurons in the lumbar 5 (L5) ganglia in the control rodents; however, |
| Ключевые слова |
Autonerve graft; Human adipose-derived stem cell (hADSC); Peripheral nerve injury; Regenerative medicine; Repair; Xenotransplantation |
| Название журнала |
Clinical and Experimental Medicine
|
| URL |
http://link.springer.com/article/10.1007%2Fs10238-015-0364-3 |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=135676 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Журавлева Маргарита Николаевна |
ru_RU |
| dc.contributor.author |
Киясов Андрей Павлович |
ru_RU |
| dc.contributor.author |
Масгутов Руслан Фаридович |
ru_RU |
| dc.contributor.author |
Масгутова Галина Андреевна |
ru_RU |
| dc.contributor.author |
Мухамедшина Яна Олеговна |
ru_RU |
| dc.contributor.author |
Мухаметшина Регина Рустамовна |
ru_RU |
| dc.contributor.author |
Ризванов Альберт Анатольевич |
ru_RU |
| dc.contributor.author |
Салафутдинов Ильнур Ильдусович |
ru_RU |
| dc.contributor.author |
Lima LM, Reis HJ, Palotás A Lima LM, Reis HJ, Palotás A |
ru_RU |
| dc.date.accessioned |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2016 |
ru_RU |
| dc.identifier.citation |
Masgutov RF Human adipose-derived stem cells stimulate neuroregeneration. Masgutov RF, Masgutova GA, Zhuravleva MN, Salafutdinov II, Mukhametshina RT, Mukhamedshina YO, Lima LM, Reis HJ, Kiyasov AP, Palotás A, Rizvanov AA.// Clin Exp Med. 2016 Aug;16(3):451-61. doi: 10.1007/s10238-015-0364-3. Epub 2015 Jun 6. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=135676 |
ru_RU |
| dc.description.abstract |
Clinical and Experimental Medicine |
ru_RU |
| dc.description.abstract |
Traumatic brain injuries and degenerative neurological disorders such as Alzheimer's dementia, Parkinson's disease, amyotrophic lateral sclerosis and many others are characterized by loss of brain cells and supporting structures. Restoring microanatomy and function using stem cells is a promising therapeutic approach. Among the many various sources, adipose-derived stem cells (ADSCs) are one of the most easily harvested alternatives, they multiply rapidly, and they demonstrate low immunogenicity with an ability to differentiate into several cell types. The objective of this study was to evaluate the effect of xenotransplanted human ADSCs on post-traumatic regeneration of rat sciatic nerve. Peripheral reconstruction following complete sciatic transection and autonerve grafting was complemented by intra-operative injection of hADSCs into the proximal and distal stumps. The injury caused gliosis and apoptosis of sensory neurons in the lumbar 5 (L5) ganglia in the control rodents; however, |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
|
ru_RU |
| dc.title |
Human adipose-derived stem cells stimulate neuroregeneration |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
EN 
中文 
ES 
Карта сайта
