| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2016 |
| Язык | английский |
|
Курбангалиева Альмира Рафаэловна, автор
|
| Библиографическое описание на языке оригинала |
Ogura A. Exploring the glycan interaction in vivo: future prospects of neo-glycoproteins for diagnostics / A. Ogura, A. Kurbangalieva, K. Tanaka // Glycobiology. - 2016. doi: 10.1093/glycob/cww038 |
| Аннотация |
Herein the biodistributions and in vivo kinetics of chemically prepared neoglycoproteins are reviewed. Chemical methods can be used to conjugate various mono- and oligosaccharides onto a protein surface. The kinetics and organ-specific accumulation profiles of these glycoconjugates, which are introduced through intravenous injections, have been analyzed using conventional dissection studies as well as noninvasive methods such as single photon emission computed tomography, positron emission tomography, and fluorescence imaging. These studies suggest that glycan-dependent protein distribution kinetics may be useful for pharmacological and diagnostic applications. |
| Ключевые слова |
albumin, in vivo imaging, neo-glycoprotein, N-glycans, tumor targeting |
| Название журнала |
Glycobiology
|
| URL |
http://glycob.oxfordjournals.org/content/early/2016/04/14/glycob.cww038.abstract |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=136147 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Курбангалиева Альмира Рафаэловна |
ru_RU |
| dc.date.accessioned |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2016 |
ru_RU |
| dc.identifier.citation |
Ogura A. Exploring the glycan interaction in vivo: future prospects of neo-glycoproteins for diagnostics / A. Ogura, A. Kurbangalieva, K. Tanaka // Glycobiology. - 2016. doi: 10.1093/glycob/cww038 |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=136147 |
ru_RU |
| dc.description.abstract |
Glycobiology |
ru_RU |
| dc.description.abstract |
Herein the biodistributions and in vivo kinetics of chemically prepared neoglycoproteins are reviewed. Chemical methods can be used to conjugate various mono- and oligosaccharides onto a protein surface. The kinetics and organ-specific accumulation profiles of these glycoconjugates, which are introduced through intravenous injections, have been analyzed using conventional dissection studies as well as noninvasive methods such as single photon emission computed tomography, positron emission tomography, and fluorescence imaging. These studies suggest that glycan-dependent protein distribution kinetics may be useful for pharmacological and diagnostic applications. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
albumin |
ru_RU |
| dc.subject |
in vivo imaging |
ru_RU |
| dc.subject |
neo-glycoprotein |
ru_RU |
| dc.subject |
N-glycans |
ru_RU |
| dc.subject |
tumor targeting |
ru_RU |
| dc.title |
Exploring the glycan interaction in vivo: future prospects of neo-glycoproteins for diagnostics |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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