| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2016 |
| Язык | английский |
|
Андрианов Вячеслав Вадимович, автор
Богодвид Татьяна Халиловна, автор
Гайнутдинов Халил Латыпович, автор
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Денисов Андрей Анатольевич, автор
Досина Маргарита Олеговна, автор
Июдин Василий Сергеевич, автор
Кульчицкий Владимир Адамович, автор
Пашкевич Светлана Георгиевна, автор
|
| Библиографическое описание на языке оригинала |
Andrianov V.V. Changes of Nitric Oxide Content in the Rat Hippocampus, Heart and Liver in Acute Phase of Ischemia / V. V. Andrianov, S. G. Pashkevich, G. G. Yafarova, A. A. Denisov, V. S. Iyudin, T. Kh. Bogodvid, M. O. Dosina, V. A. Kulchitsky, Kh. L. Gainutdinov // Appl. Magn. Reson. - 2016. - V. 47. - N 9. - P. 965-976. |
| Аннотация |
Electron paramagnetic resonance (EPR) was used as a method to record nitric oxide (NO) production in the tissues of the brain, heart and liver of healthy rats, and rats after modeling of ischemic stroke. Direct measurement of the dynamics of NO production by EPR spectroscopy in our experiments showed that after the emergence of signs of ischemic stroke, 5 hours after the start of ischemia, the content of NO in the hippocampus decreased 2-3 fold and this decrease was maintained at 24 and 72 hours. Deserving special attention is the data demonstrating that there is a greater decrease of NO production in the tissues of the heart and liver than in the brain. Consequently, the change in intensity of NO production in the modeling of ischemic events in the brain has a systemic, not a local character. |
| Ключевые слова |
nitric oxide, electron paramagnetic resonance, spin trap, ischemic brain stroke |
| Название журнала |
APPLIED MAGNETIC RESONANCE
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https://repository.kpfu.ru/?p_id=138581 |
| Файлы ресурса | |
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Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Андрианов Вячеслав Вадимович |
ru_RU |
| dc.contributor.author |
Богодвид Татьяна Халиловна |
ru_RU |
| dc.contributor.author |
Гайнутдинов Халил Латыпович |
ru_RU |
| dc.contributor.author |
Денисов Андрей Анатольевич |
ru_RU |
| dc.contributor.author |
Досина Маргарита Олеговна |
ru_RU |
| dc.contributor.author |
Июдин Василий Сергеевич |
ru_RU |
| dc.contributor.author |
Кульчицкий Владимир Адамович |
ru_RU |
| dc.contributor.author |
Пашкевич Светлана Георгиевна |
ru_RU |
| dc.date.accessioned |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2016-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2016 |
ru_RU |
| dc.identifier.citation |
Andrianov V.V. Changes of Nitric Oxide Content in the Rat Hippocampus, Heart and Liver in Acute Phase of Ischemia / V. V. Andrianov, S. G. Pashkevich, G. G. Yafarova, A. A. Denisov, V. S. Iyudin, T. Kh. Bogodvid, M. O. Dosina, V. A. Kulchitsky, Kh. L. Gainutdinov // Appl. Magn. Reson. - 2016. - V. 47. - N 9. - P. 965-976. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=138581 |
ru_RU |
| dc.description.abstract |
APPLIED MAGNETIC RESONANCE |
ru_RU |
| dc.description.abstract |
Electron paramagnetic resonance (EPR) was used as a method to record nitric oxide (NO) production in the tissues of the brain, heart and liver of healthy rats, and rats after modeling of ischemic stroke. Direct measurement of the dynamics of NO production by EPR spectroscopy in our experiments showed that after the emergence of signs of ischemic stroke, 5 hours after the start of ischemia, the content of NO in the hippocampus decreased 2-3 fold and this decrease was maintained at 24 and 72 hours. Deserving special attention is the data demonstrating that there is a greater decrease of NO production in the tissues of the heart and liver than in the brain. Consequently, the change in intensity of NO production in the modeling of ischemic events in the brain has a systemic, not a local character. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
nitric oxide |
ru_RU |
| dc.subject |
electron paramagnetic resonance |
ru_RU |
| dc.subject |
spin trap |
ru_RU |
| dc.subject |
ischemic brain stroke |
ru_RU |
| dc.title |
Changes of Nitric Oxide Content in the Rat Hippocampus, Heart and Liver in Acute Phase of Ischemia |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
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