| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2017 |
| Язык | английский |
|
Латыпова Лилия Зиннуровна, автор
|
| Библиографическое описание на языке оригинала |
Latypova, L. Sequential double “clicks” toward structurally well-defined heterogeneous N-glycoclusters: the importance of cluster heterogeneity on pattern recognition in vivo / L. Latypova, R. Sibgatullina, A. Ogura, K. Fujiki, A. Khabibrakhmanova, T. Tahara, S. Nozaki, S. Urano, K. Tsubokura, H. Onoe, Y. Watanabe, A. Kurbangalieva, K. Tanaka. // Advanced Science – 2017. – V. 4. – № 2. doi: 10.1002/advs.201600394 |
| Аннотация |
Two structurally distinct N-glycans were initially united in a single azide-terminated compound that was then immobilized onto albumin via a double click procedure. Noninvasive imaging data revealed that the excretion pathway of the structurally well-defined heterogeneous glycoclusters was not simply a combination of the excretion pathways taken by the homogeneous or arbitrarily arranged heterogeneous glycoclusters. The number of glycan molecules present, in addition to the spatial arrangement of glycans in the heterogeneous glycoclusters, played an important role in the in vivo kinetics and organ-selective accumulation through glycan pattern recognition mechanisms. |
| Ключевые слова |
N-glycoalbumin, heterogeneity, pattern recognition, in vivo kinetics, biodistribution, noninvasive fluorescence imaging |
| Название журнала |
Advanced Science
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=151881 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Латыпова Лилия Зиннуровна |
ru_RU |
| dc.date.accessioned |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2017 |
ru_RU |
| dc.identifier.citation |
Latypova, L. Sequential double “clicks” toward structurally well-defined heterogeneous N-glycoclusters: the importance of cluster heterogeneity on pattern recognition in vivo / L. Latypova, R. Sibgatullina, A. Ogura, K. Fujiki, A. Khabibrakhmanova, T. Tahara, S. Nozaki, S. Urano, K. Tsubokura, H. Onoe, Y. Watanabe, A. Kurbangalieva, K. Tanaka. // Advanced Science – 2017. – V. 4. – № 2. doi: 10.1002/advs.201600394 |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=151881 |
ru_RU |
| dc.description.abstract |
Advanced Science |
ru_RU |
| dc.description.abstract |
Two structurally distinct N-glycans were initially united in a single azide-terminated compound that was then immobilized onto albumin via a double click procedure. Noninvasive imaging data revealed that the excretion pathway of the structurally well-defined heterogeneous glycoclusters was not simply a combination of the excretion pathways taken by the homogeneous or arbitrarily arranged heterogeneous glycoclusters. The number of glycan molecules present, in addition to the spatial arrangement of glycans in the heterogeneous glycoclusters, played an important role in the in vivo kinetics and organ-selective accumulation through glycan pattern recognition mechanisms. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
N-glycoalbumin |
ru_RU |
| dc.subject |
heterogeneity |
ru_RU |
| dc.subject |
pattern recognition |
ru_RU |
| dc.subject |
in vivo kinetics |
ru_RU |
| dc.subject |
biodistribution |
ru_RU |
| dc.subject |
noninvasive fluorescence imaging |
ru_RU |
| dc.title |
Sequential double “clicks” toward structurally well-defined heterogeneous N-glycoclusters: the importance of cluster heterogeneity on pattern recognition in vivo |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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