Казанский (Приволжский) федеральный университет, КФУ
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ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ
 
SUPERSTATISTICAL MODEL OF BACTERIAL DNA ARCHITECTURE
Форма представленияСтатьи в зарубежных журналах и сборниках
Год публикации2017
Языканглийский
  • Богачев Михаил Игоревич, автор
  • Каюмов Айрат Рашитович, автор
  • Markelov O. A., автор
  • Библиографическое описание на языке оригинала Bogachev M.I. Superstatistical model of bacterial DNA architecture / Bogachev M.I., Markelov O.A., Kayumov A.R. // Scientific Reports. - 2017. - V.7. - Art. № 43034.
    Аннотация Understanding the physical principles that govern the complex DNA structural organization as well as its mechanical and thermodynamical properties is essential for the advancement in both life sciences and genetic engineering. Recently we have discovered that the complex DNA organization is explicitly reflected in the arrangement of nucleotides depicted by the universal power law tailed internucleotide interval distribution that is valid for complete genomes of various prokaryotic and eukaryotic organisms. Here we suggest a superstatistical model that represents a long DNA molecule by a series of consecutive ~150 bp DNA segments with the alternation of the local nucleotide composition between segments exhibiting long-range correlations. We show that the superstatistical model and the corresponding DNA generation algorithm explicitly reproduce the laws governing the empirical nucleotide arrangement properties of the DNA sequences for various global GC contents and optimal living tempera
    Ключевые слова DNA
    Название журнала SCIENTIFIC REPORTS
    URL https://www.nature.com/articles/srep43034
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