КФУ. Карточка публикации. Lysozyme in water-acetonitrile mixtures: Preferential solvation at the inner edge of excess hydration

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LYSOZYME IN WATER-ACETONITRILE MIXTURES: PREFERENTIAL SOLVATION AT THE INNER EDGE OF EXCESS HYDRATION

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2017

Язык

английский

Авторы, сотрудники КФУ

Сироткин Владимир Александрович, автор

Авторы, студенты КФУ

Кучиерская Александра Александровна, автор

Библиографическое описание на языке оригинала

Sirotkin, V.A. Lysozyme in water-acetonitrile mixtures: Preferential solvation at the inner edge of excess hydration. [Text] / V. A. Sirotkin, A.A. Kuchierskaya // Journal of Chemical Physics. - 2017. - Vol. 146. - P. 215101-8. ISSN: 0021-9606

Аннотация

Preferential solvation/hydration is an effective way for regulating the mechanism of the protein destabilization/stabilization. Organic solvent/water sorption and residual enzyme activity measurements were performed to monitor the preferential solvation/hydration of hen egg-white lysozyme at high and low water content in acetonitrile at 25 ?C. The obtained results show that the protein destabilization/stabilization depends essentially on the initial hydration level of lysozyme and the water content in acetonitrile.

Ключевые слова

Preferential solvation, Protein hydration, Lysozyme, Acetonitrile, Water

Название журнала

J CHEM PHYS

URL

http://dx.doi.org/10.1063/1.4984116

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https://repository.kpfu.ru/?p_id=158511

Файлы ресурса

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JCP_2017_Accepted_MS.pdf	3,50	pdf	посмотреть / скачать

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Сироткин Владимир Александрович	ru_RU
dc.contributor.author	Кучиерская Александра Александровна	ru_RU
dc.date.accessioned	2017-01-01T00:00:00Z	ru_RU
dc.date.available	2017-01-01T00:00:00Z	ru_RU
dc.date.issued	2017	ru_RU
dc.identifier.citation	Sirotkin, V.A. Lysozyme in water-acetonitrile mixtures: Preferential solvation at the inner edge of excess hydration. [Text] / V. A. Sirotkin, A.A. Kuchierskaya // Journal of Chemical Physics. - 2017. - Vol. 146. - P. 215101-8. ISSN: 0021-9606	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=158511	ru_RU
dc.description.abstract	J CHEM PHYS	ru_RU
dc.description.abstract	Preferential solvation/hydration is an effective way for regulating the mechanism of the protein destabilization/stabilization. Organic solvent/water sorption and residual enzyme activity measurements were performed to monitor the preferential solvation/hydration of hen egg-white lysozyme at high and low water content in acetonitrile at 25 ?C. The obtained results show that the protein destabilization/stabilization depends essentially on the initial hydration level of lysozyme and the water content in acetonitrile.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Preferential solvation	ru_RU
dc.subject	Protein hydration	ru_RU
dc.subject	Lysozyme	ru_RU
dc.subject	Acetonitrile	ru_RU
dc.subject	Water	ru_RU
dc.title	Lysozyme in water-acetonitrile mixtures: Preferential solvation at the inner edge of excess hydration	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU