| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2017 |
| Язык | английский |
|
Шуралев Эдуард Аркадьевич, автор
|
|
Braun Yvonne , автор
Elamin Ayssar A. , автор
Huck Carmen , автор
Maringer Marko , автор
Oehlmann Wulf , автор
Rohde Manfred , автор
Singh Mahavir , автор
Steinicke Susanne , автор
Wanas Hanaa , автор
|
| Библиографическое описание на языке оригинала |
Elamin A.A. Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa / A.A. Elamin, S. Steinicke, W. Oehlmann, Y. Braun, H. Wanas, E.A. Shuralev, C. Huck, M. Maringer, M. Rohde, M. Singh // PLoS ONE. - 2017. - 12(10): e0186801. DOI: 10.1371/journal.pone.0186801. WOS:000413168100091 |
| Аннотация |
This study demonstrates that cell wall targets contribute significantly to intracellular survival, in vivo growth, and pathogenesis of P. aeruginosa. In conclusion, these findings establish a link between cell wall targets and virulence of P. aeruginosa and thus may lead to development of novel drugs for the treatment of P. aeruginosa infection. |
| Ключевые слова |
ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, BACTERIAL BIOFILM FORMATION, UDP-N-ACETYLGLUCOSAMINE, ESCHERICHIA-COLI, VIRULENCE FACTORS; LIPOPOLYSACCHARIDE BIOSYNTHESIS; OPPORTUNISTIC PATHOGEN, CRYSTAL-STRUCTURE, ENDOTOXINS, ANTIBIOTICS |
| Название журнала |
PLos ONE
|
| Ссылка для РПД |
http://dspace.kpfu.ru/xmlui/bitstream/handle/net/117107/F_Shuralev_Pseudomona.pdf?sequence=1&isAllowed=y
|
| URL |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186801 |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=167144 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Шуралев Эдуард Аркадьевич |
ru_RU |
| dc.contributor.author |
Braun Yvonne |
ru_RU |
| dc.contributor.author |
Elamin Ayssar A. |
ru_RU |
| dc.contributor.author |
Huck Carmen |
ru_RU |
| dc.contributor.author |
Maringer Marko |
ru_RU |
| dc.contributor.author |
Oehlmann Wulf |
ru_RU |
| dc.contributor.author |
Rohde Manfred |
ru_RU |
| dc.contributor.author |
Singh Mahavir |
ru_RU |
| dc.contributor.author |
Steinicke Susanne |
ru_RU |
| dc.contributor.author |
Wanas Hanaa |
ru_RU |
| dc.date.accessioned |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2017 |
ru_RU |
| dc.identifier.citation |
Elamin A.A. Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa / A.A. Elamin, S. Steinicke, W. Oehlmann, Y. Braun, H. Wanas, E.A. Shuralev, C. Huck, M. Maringer, M. Rohde, M. Singh // PLoS ONE. - 2017. - 12(10): e0186801. DOI: 10.1371/journal.pone.0186801. WOS:000413168100091 |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=167144 |
ru_RU |
| dc.description.abstract |
PLos ONE |
ru_RU |
| dc.description.abstract |
This study demonstrates that cell wall targets contribute significantly to intracellular survival, in vivo growth, and pathogenesis of P. aeruginosa. In conclusion, these findings establish a link between cell wall targets and virulence of P. aeruginosa and thus may lead to development of novel drugs for the treatment of P. aeruginosa infection. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE |
ru_RU |
| dc.subject |
BACTERIAL BIOFILM FORMATION |
ru_RU |
| dc.subject |
UDP-N-ACETYLGLUCOSAMINE |
ru_RU |
| dc.subject |
ESCHERICHIA-COLI |
ru_RU |
| dc.subject |
VIRULENCE FACTORS; LIPOPOLYSACCHARIDE BIOSYNTHESIS; OPPORTUNISTIC PATHOGEN |
ru_RU |
| dc.subject |
CRYSTAL-STRUCTURE |
ru_RU |
| dc.subject |
ENDOTOXINS |
ru_RU |
| dc.subject |
ANTIBIOTICS |
ru_RU |
| dc.title |
Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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