| Форма представления | Статьи в российских журналах и сборниках |
| Год публикации | 2017 |
| Язык | английский |
|
Хамидуллина Раиса Гусмановна, автор
|
| Библиографическое описание на языке оригинала |
Maxim V. TRUSHIN, Raisa G. KHAMIDULLINA,Oleg V. ARDASHOV,Konstantin P. VOLCHO2,Nariman F. SALAKHUTDINOV. The action of monoterpenoids with promising antiparkinsonian activity on fertility of Drosophila melanogaster // Marmara Pharmaceutical Journal 21/4: 987-991, 2017. DOI: 10.12991/mpj.2017.29 |
| Аннотация |
Adequate treatment of Parkinson's disease is an important
medical issue. Patients are suffered from numerous side
effects of the widely used drugs. It has been found recently
that monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)
cyclohex-3-ene-1,2-diol and its diacetate demonstrate high
antiparkinsonian activity in some animal models. At the same
time, their genetic safety was not studied yet. The aim of this
research was to investigate the effect of these compounds with
antiparkinsonian activities on reproduction of D. melanogaster.
Over 4000 of fruitflies cultivated under the action of these
compounds were analyzed. It was found that the chemicals
did not provoke genetic mutations or alter reproduction of
D. melanogaster. The possible explanations for the detected
phenomena are provided. It was found that the compounds do
not affect fertility in Drosophila.. |
| Ключевые слова |
Parkinson?s disease; fertility; drosophila; (1R,2R,6S)-
3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol; acetate; |
| Название журнала |
Marmara Pharmaceutical Journal
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=168457 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Хамидуллина Раиса Гусмановна |
ru_RU |
| dc.date.accessioned |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2017-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2017 |
ru_RU |
| dc.identifier.citation |
Maxim V. TRUSHIN, Raisa G. KHAMIDULLINA,Oleg V. ARDASHOV,Konstantin P. VOLCHO2,Nariman F. SALAKHUTDINOV. The action of monoterpenoids with promising antiparkinsonian activity on fertility of Drosophila melanogaster // Marmara Pharmaceutical Journal 21/4: 987-991, 2017. DOI: 10.12991/mpj.2017.29 |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=168457 |
ru_RU |
| dc.description.abstract |
Marmara Pharmaceutical Journal |
ru_RU |
| dc.description.abstract |
Adequate treatment of Parkinson's disease is an important
medical issue. Patients are suffered from numerous side
effects of the widely used drugs. It has been found recently
that monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)
cyclohex-3-ene-1,2-diol and its diacetate demonstrate high
antiparkinsonian activity in some animal models. At the same
time, their genetic safety was not studied yet. The aim of this
research was to investigate the effect of these compounds with
antiparkinsonian activities on reproduction of D. melanogaster.
Over 4000 of fruitflies cultivated under the action of these
compounds were analyzed. It was found that the chemicals
did not provoke genetic mutations or alter reproduction of
D. melanogaster. The possible explanations for the detected
phenomena are provided. It was found that the compounds do
not affect fertility in Drosophila.. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Parkinson?s disease; fertility; drosophila; (1R |
ru_RU |
| dc.subject |
2R |
ru_RU |
| dc.subject |
6S)-
3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1 |
ru_RU |
| dc.subject |
2-diol; acetate; |
ru_RU |
| dc.title |
The action of monoterpenoids with promising antiparkinsonian activity on fertility of Drosophila melanogaster |
ru_RU |
| dc.type |
Статьи в российских журналах и сборниках |
ru_RU |
|
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