Казанский (Приволжский) федеральный университет, КФУ
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PHOTODYNAMIC EFFECT OF FOTODITAZIN ON THE DNA AND THE NUCLEI OF ERYTHROCYTES OF BRACHYDANIO RERIO
Форма представленияСтатьи в зарубежных журналах и сборниках
Год публикации2017
Языканглийский
  • Леонтьев Вячеслав Витальевич, автор
  • Библиографическое описание на языке оригинала Purtskhvanidze V.A, Simakov Y.G, Omelchuk N.N, Talismanov V.S., Leontyev V.V. Photodynamic effect of fotoditazin on the DNA and the nuclei of erythrocytes of Brachydanio rerio // Journal of Pharmaceutical Sciences and Research. - 2017. - Vol.9, Is.7. - P.1250-1254.
    Аннотация The study is aimed at identifying the morphological and cytogenetic changes in erythrocytes of Brachydanio rerio, arising under the influence of photodynamic effects that models laser modification of blood, with the use of Fotoditazin, a photosensitizer of the chlorine range, and red laser radiation. (Methods of Research) For 15 days, juvenile fish Brachydanio rerio were kept in settled tap water after providing model of laser modification of the blood using Fotoditazin and exposure to laser radiation with the wavelength of 630 nm. The impact on the structure of DNA in the nuclei of red blood cells of Fotoditazin, laser radiation and combined effects of these factors on the changes in the fluorescence spectra of DNA and the color of fluorescence were studied.(Generalization of results and their meaning). It had been shown that separate effects of laser or Fotoditazin did not cause changes in the fluorescence of nuclei of erythrocytes, when the preparations were studied with the use of
    Ключевые слова Fotoditazin, laser radiation, fish erythrocytes? nuclei, acridine orange, nuclei fluorescence, changes in the DNA structure, nuclei polymorphism
    Название журнала Journal of Pharmaceutical Sciences and Research
    URL https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026659735&partnerID=40&md5=91063ab2763010a0733e0b48f1937130
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