Казанский (Приволжский) федеральный университет, КФУ
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TUBULAR NANOCONTAINERS FOR DRUG DELIVERY
Форма представленияЗарубежные монографии
Год публикации2018
Языканглийский
  • Науменко Екатерина Анатольевна, автор
  • Фахруллин Равиль Фаридович, автор
  • Библиографическое описание на языке оригинала Darrat Y.Tubular Nanocontainers for Drug Delivery/ Darrat Y., Naumenko E. Cavallaro G., Lazzara G., Lvov Yu. , Fakhrullin R. Chapter 4 in book: Materials Nanoarchitectonics; Editos: Dr Katsuhiko Ariga, Dr Mitsuhiro Ebara.- Wiley‐VCH Verlag GmbH & Co. KGaA, 2018, - P. 85-108. https://doi.org/10.1002/9783527808311.ch4
    Аннотация This chapter overviews the use of two types of nanotubular materials, namely, carbon nanotubes (CNTs) and halloysite clay nanotubes (HCTs) for fabrication of nano‐architectonic drug delivery platforms. It then discusses the uptake mechanisms of intracellular uptake of nanocontainers having tubular geometry. In addition to functionalization, CNTs can be used to synthesize hybrid materials. The cyclodextrin (CD) glycocluster/Halloysite nanotubes (HNTs) showed efficient carrier ability toward silibinin and curcumin, which present a pH‐dependent affinity toward the functionalized nanotubes. Functionalized CNTs can be useful for vaccine treatment, gene therapy, drug delivery, and other pharmaceutical applications. The functionalized HNTs were employed as dual‐responsive nanocarriers. HCTs are a natural nanosized material currently used in fabrication of drug delivery vehicles. Both CNTs and HNTs are considered as transporters for various cargos including medical formulations for target drug delivery. The preparation of the dual drug delivery system was based on a green protocol using absolvent‐free microwave irradiation.
    Ключевые слова Halloysite nanotubes, drug delivery, carbon nanotubes
    URL https://onlinelibrary.wiley.com/doi/abs/10.1002/9783527808311.ch4
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