| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2019 |
| Язык | английский |
|
Белушкин Александр Владиславович, автор
|
|
Feldman Tatiana , автор
Gordeliy Valentin , автор
Ivankov Oleksandr , автор
Kolchugina Irina , автор
Kuklin Alexander , автор
Murugova Tatiana , автор
Ostrovsky Mikhail , автор
Round Adam , автор
Smitienko Olga , автор
Yakovleva Marina , автор
|
| Библиографическое описание на языке оригинала |
Tatiana B. Feldman Small-angle neutron and X-ray scattering analysis of the supramolecular organization of rhodopsin in photoreceptor membrane /Tatiana B. Feldmana, Oleksandr I. Ivankovc, Alexander I. Kuklin, Tatiana N. Murugova,
Marina A. Yakovleva, Olga A. Smitienko, Irina B. Kolchugina, Adam Round, Valentin I. Gordeliy, Alexander V. Belushkin, Mikhail A. Ostrovsky // Biochimica et Biophysica Acta (BBA) - Biomembranes. - 2019. - 1861. - 183000-183006. |
| Аннотация |
The supramolecular organization of the visual pigment rhodopsin in the photoreceptor membrane remains
contentious. Specifically, whether this G protein-coupled receptor functions as a monomer or dimer remains
unknown, as does the presence or absence of ordered packing of rhodopsin molecules in the photoreceptor
membrane. Completely opposite opinions have been expressed on both issues. Herein, using small-angle neutron
and X-ray scattering approaches, we performed a comparative analysis of the structural characteristics of the
photoreceptor membrane samples in buffer, both in the outer segment of photoreceptor cells, and in the free
photoreceptor disks. The average distance between the centers of two neighboring rhodopsin molecules was
found to be ~5.8 nm in both cases. The results indicate an unusually high packing density of rhodopsin molecules
in the photoreceptor membrane, but molecules appear to be randomly distributed in the membrane
without any regular ordering. |
| Ключевые слова |
Rhodopsin, Photoreceptor membrane, Oligomerization,
Supramolecular organization, SANS, SAXS |
| Название журнала |
Biochimica et Biophysica Acta - Biomembranes
|
| URL |
https://www.sciencedirect.com/science/article/pii/S0005273619301191?dgcid=coauthor |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=206809 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Белушкин Александр Владиславович |
ru_RU |
| dc.contributor.author |
Feldman Tatiana |
ru_RU |
| dc.contributor.author |
Gordeliy Valentin |
ru_RU |
| dc.contributor.author |
Ivankov Oleksandr |
ru_RU |
| dc.contributor.author |
Kolchugina Irina |
ru_RU |
| dc.contributor.author |
Kuklin Alexander |
ru_RU |
| dc.contributor.author |
Murugova Tatiana |
ru_RU |
| dc.contributor.author |
Ostrovsky Mikhail |
ru_RU |
| dc.contributor.author |
Round Adam |
ru_RU |
| dc.contributor.author |
Smitienko Olga |
ru_RU |
| dc.contributor.author |
Yakovleva Marina |
ru_RU |
| dc.date.accessioned |
2019-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2019-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2019 |
ru_RU |
| dc.identifier.citation |
Tatiana B. Feldman Small-angle neutron and X-ray scattering analysis of the supramolecular organization of rhodopsin in photoreceptor membrane /Tatiana B. Feldmana, Oleksandr I. Ivankovc, Alexander I. Kuklin, Tatiana N. Murugova,
Marina A. Yakovleva, Olga A. Smitienko, Irina B. Kolchugina, Adam Round, Valentin I. Gordeliy, Alexander V. Belushkin, Mikhail A. Ostrovsky // Biochimica et Biophysica Acta (BBA) - Biomembranes. - 2019. - 1861. - 183000-183006. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=206809 |
ru_RU |
| dc.description.abstract |
Biochimica et Biophysica Acta - Biomembranes |
ru_RU |
| dc.description.abstract |
The supramolecular organization of the visual pigment rhodopsin in the photoreceptor membrane remains
contentious. Specifically, whether this G protein-coupled receptor functions as a monomer or dimer remains
unknown, as does the presence or absence of ordered packing of rhodopsin molecules in the photoreceptor
membrane. Completely opposite opinions have been expressed on both issues. Herein, using small-angle neutron
and X-ray scattering approaches, we performed a comparative analysis of the structural characteristics of the
photoreceptor membrane samples in buffer, both in the outer segment of photoreceptor cells, and in the free
photoreceptor disks. The average distance between the centers of two neighboring rhodopsin molecules was
found to be ~5.8 nm in both cases. The results indicate an unusually high packing density of rhodopsin molecules
in the photoreceptor membrane, but molecules appear to be randomly distributed in the membrane
without any regular ordering. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Rhodopsin |
ru_RU |
| dc.subject |
Photoreceptor membrane |
ru_RU |
| dc.subject |
Oligomerization |
ru_RU |
| dc.subject |
Supramolecular organization |
ru_RU |
| dc.subject |
SANS |
ru_RU |
| dc.subject |
SAXS |
ru_RU |
| dc.title |
Small-angle neutron and X-ray scattering analysis of the supramolecular organization of rhodopsin in photoreceptor membrane |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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