КФУ. Карточка публикации. The State of the Nitric Oxide Cycle in Respiratory Tract Diseases.

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THE STATE OF THE NITRIC OXIDE CYCLE IN RESPIRATORY TRACT DISEASES.

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2020

Язык

английский

Авторы, сотрудники КФУ

Кубышева Наиля Исхаковна, автор

Другие авторы

Batyrshin Ildar , автор

Klimanov Igor , автор

Popova Nataliia , автор

Soodaeva Svetlana , автор

Библиографическое описание на языке оригинала

Soodaeva, S., Klimanov, I., Kubysheva, N., Popova, N., & Batyrshin, I. (2020). The State of the Nitric Oxide Cycle in Respiratory Tract Diseases. Oxidative Medicine and Cellular Longevity, 2020.

Аннотация

Oxidative medicine and cellular longevity

Ключевые слова

Nitric oxide cycle, respiratory disease

Название журнала

Oxidative medicine and cellular longevity

URL

https://www.hindawi.com/journals/omcl/2020/4859260/

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https://repository.kpfu.ru/?p_id=240867

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Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Кубышева Наиля Исхаковна	ru_RU
dc.contributor.author	Batyrshin Ildar	ru_RU
dc.contributor.author	Klimanov Igor	ru_RU
dc.contributor.author	Popova Nataliia	ru_RU
dc.contributor.author	Soodaeva Svetlana	ru_RU
dc.date.accessioned	2020-01-01T00:00:00Z	ru_RU
dc.date.available	2020-01-01T00:00:00Z	ru_RU
dc.date.issued	2020	ru_RU
dc.identifier.citation	Soodaeva, S., Klimanov, I., Kubysheva, N., Popova, N., & Batyrshin, I. (2020). The State of the Nitric Oxide Cycle in Respiratory Tract Diseases. Oxidative Medicine and Cellular Longevity, 2020.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=240867	ru_RU
dc.description.abstract	Oxidative medicine and cellular longevity	ru_RU
dc.description.abstract	This review describes the unique links of the functioning of the nitric oxide cycle in the respiratory tract in normal and pathological conditions. The concept of a nitric oxide cycle has been expanded to include the NO-synthase and NO-synthase-independent component of its synthesis and the accompanying redox cascades in varying degrees of reversible reactions. The role of non-NO-synthase cycle components has been shown. Detailed characteristics of substrates for the synthesis of nitric oxide (NO) in the human body, which can be nitrogen oxides, nitrite and nitrate anions, and organic nitrates, as well as nitrates and nitrites of food products, are given. The importance of the human microbiota in the nitric oxide cycle has been shown. The role of significant components of nitrite and nitrate reductase systems in the nitric oxide cycle and the mechanisms of their activation and deactivation (participation of enzymes, cofactors, homeostatic indicators, etc.) under various conditions have been determined. Consideration of these factors allows for a detailed understanding of the mechanisms underlying pathological conditions of the respiratory system and the targeting of therapeutic agents. The complexity of the NO cycle with multidirectional cascades could be best understood using dynamic modeling.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Nitric oxide cycle	ru_RU
dc.subject	respiratory disease	ru_RU
dc.title	The State of the Nitric Oxide Cycle in Respiratory Tract Diseases.	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU