| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2020 |
| Язык | английский |
|
Ризванов Альберт Анатольевич, автор
Шафигуллина Айгуль Касыймовна, автор
|
|
Guida Bento , автор
Macedo Maria Paula , автор
Oliveira Paulo J. , автор
Sardão Vilma A. , автор
|
| Библиографическое описание на языке оригинала |
Guida Bento et al. Urine-Derived Stem Cells: Applications in Regenerative and Predictive Medicine / Guida Bento, Aygul K. Shafigullina, Albert A. Rizvanov, Vilma A. Sardão, Maria Paula Macedo and Paulo J. Oliveira // Cells. 2020 Mar; 9(3): 573. |
| Аннотация |
Despite being a biological waste, human urine contains a small population of cells with
self-renewal capacity and differentiation potential into several cell types. Being derived from the
convoluted tubules of nephron, renal pelvis, ureters, bladder and urethra, urine-derived stem cells
(UDSC) have a similar phenotype to mesenchymal stroma cells (MSC) and can be reprogrammed
into iPSC (induced pluripotent stem cells). Having simple, safer, low-cost and noninvasive collection
procedures, the interest in UDSC has been growing in the last decade. With great potential in
regenerative medicine applications, UDSC can also be used as biological models for pharmacology
and toxicology tests. This review describes UDSC biological characteristics and differentiation
potential and their possible use, including the potential of UDSC-derived iPSC to be used in drug
discovery and toxicology, as well as in regenerative medicine. Being a new cellular platform
amenable to noninvasive collection for disease stratification and personalized therapy could be a
future application for UDSC. |
| Ключевые слова |
urine-derived stem cells; personalized medicine; regenerative medicine; induced-pluripotent
stem cells |
| Название журнала |
CELLS
|
| URL |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140531/ |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=240972 |
| Файлы ресурса | |
|
|
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Ризванов Альберт Анатольевич |
ru_RU |
| dc.contributor.author |
Шафигуллина Айгуль Касыймовна |
ru_RU |
| dc.contributor.author |
Guida Bento |
ru_RU |
| dc.contributor.author |
Macedo Maria Paula |
ru_RU |
| dc.contributor.author |
Oliveira Paulo J. |
ru_RU |
| dc.contributor.author |
Sardão Vilma A. |
ru_RU |
| dc.date.accessioned |
2020-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2020-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2020 |
ru_RU |
| dc.identifier.citation |
Guida Bento et al. Urine-Derived Stem Cells: Applications in Regenerative and Predictive Medicine / Guida Bento, Aygul K. Shafigullina, Albert A. Rizvanov, Vilma A. Sardão, Maria Paula Macedo and Paulo J. Oliveira // Cells. 2020 Mar; 9(3): 573. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=240972 |
ru_RU |
| dc.description.abstract |
CELLS |
ru_RU |
| dc.description.abstract |
Despite being a biological waste, human urine contains a small population of cells with
self-renewal capacity and differentiation potential into several cell types. Being derived from the
convoluted tubules of nephron, renal pelvis, ureters, bladder and urethra, urine-derived stem cells
(UDSC) have a similar phenotype to mesenchymal stroma cells (MSC) and can be reprogrammed
into iPSC (induced pluripotent stem cells). Having simple, safer, low-cost and noninvasive collection
procedures, the interest in UDSC has been growing in the last decade. With great potential in
regenerative medicine applications, UDSC can also be used as biological models for pharmacology
and toxicology tests. This review describes UDSC biological characteristics and differentiation
potential and their possible use, including the potential of UDSC-derived iPSC to be used in drug
discovery and toxicology, as well as in regenerative medicine. Being a new cellular platform
amenable to noninvasive collection for disease stratification and personalized therapy could be a
future application for UDSC. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
|
ru_RU |
| dc.title |
Urine-Derived Stem Cells: Applications in Regenerative and Predictive Medicine |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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