Форма представления | Статьи в зарубежных журналах и сборниках |
Год публикации | 2019 |
Язык | английский |
|
Губайдуллин Айдар Тимергалиевич, автор
Коновалов Александр Иванович, автор
Морозова Юлия Эрнестовна, автор
Сайфина Алина Фуадовна, автор
Шалаева Яна Викторовна, автор
|
|
Базанова Ольга Борисовна, автор
Волошина Александра Дмитриевна, автор
Кадиров Марсил Кахирович, автор
Низамеев Ирек Рашатович, автор
Сапунова Анастасия Сергеевна, автор
Сякаев Виктор Васильевич, автор
|
|
Шуматбаева Алина Марселовна, автор
|
Библиографическое описание на языке оригинала |
A. M. Shumatbaeva, The novel calix[4]resorcinarene-PEG conjugate: Synthesis, self-association and encapsulation properties / A. M. Shumatbaeva, Ju. E. Morozova, Ya.V. Shalaeva, A.T. Gubaidullin, A.F. Saifina, V.V. Syakaev, O.B. Bazanova, A.S. Sapunova, A.D. Voloshina, I. R. Nizameev, M.K. Kadirov, A. I. Konovalov. // Colloids and Surfaces A. - 2019. – V.570. – P. 182–190. DOI: 10.1016/j.colsurfa.2019.03.021 |
Аннотация |
The synthesis and study of self-association and encapsulation ability of new low toxic conjugate of tetra-phenyleneoxypentylcalix[4]resorcinarene and methoxy-poly(ethylene glycole) (C 5 OPh-mPEG) were described.
The conjugate is characterized by 1 H, 13 C NMR, FT-IR, MS, SLS methods. In an aqueous solution the conjugate form multimicellar nanoparticles with low polydispersity value (0.1, DLS method). The self-association of the conjugate was studied by DLS, fluorescence, fluorescence anisotropy method, TEM, and SAXS methods. The SAXS data were detailed analyzed, and the conjugate associates structure as ellipsoidal core-shell particles was proposed. The encapsulation efficiency is a result of the affinity of the conjugate low rim substituents to substrates and reaches of 39.8, 26.7, and 28.9% toward naproxen, ibuprofen and doxorubicin drugs, respectively. |
Ключевые слова |
Calix[4]resorcinarene, PEG, conjugation, SAXS, encapsulation |
Название журнала |
Colloids and Surfaces A: Physicochemical and Engineering Aspects
|
URL |
https://www.sciencedirect.com/science/article/pii/S0927775719302092?via%3Dihub |
Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=241493 |
Полная запись метаданных |
Поле DC |
Значение |
Язык |
dc.contributor.author |
Губайдуллин Айдар Тимергалиевич |
ru_RU |
dc.contributor.author |
Коновалов Александр Иванович |
ru_RU |
dc.contributor.author |
Морозова Юлия Эрнестовна |
ru_RU |
dc.contributor.author |
Сайфина Алина Фуадовна |
ru_RU |
dc.contributor.author |
Шалаева Яна Викторовна |
ru_RU |
dc.contributor.author |
Базанова Ольга Борисовна |
ru_RU |
dc.contributor.author |
Волошина Александра Дмитриевна |
ru_RU |
dc.contributor.author |
Кадиров Марсил Кахирович |
ru_RU |
dc.contributor.author |
Низамеев Ирек Рашатович |
ru_RU |
dc.contributor.author |
Сапунова Анастасия Сергеевна |
ru_RU |
dc.contributor.author |
Сякаев Виктор Васильевич |
ru_RU |
dc.contributor.author |
Шуматбаева Алина Марселовна |
ru_RU |
dc.date.accessioned |
2019-01-01T00:00:00Z |
ru_RU |
dc.date.available |
2019-01-01T00:00:00Z |
ru_RU |
dc.date.issued |
2019 |
ru_RU |
dc.identifier.citation |
A. M. Shumatbaeva, The novel calix[4]resorcinarene-PEG conjugate: Synthesis, self-association and encapsulation properties / A. M. Shumatbaeva, Ju. E. Morozova, Ya.V. Shalaeva, A.T. Gubaidullin, A.F. Saifina, V.V. Syakaev, O.B. Bazanova, A.S. Sapunova, A.D. Voloshina, I. R. Nizameev, M.K. Kadirov, A. I. Konovalov. // Colloids and Surfaces A. - 2019. – V.570. – P. 182–190. DOI: 10.1016/j.colsurfa.2019.03.021 |
ru_RU |
dc.identifier.uri |
https://repository.kpfu.ru/?p_id=241493 |
ru_RU |
dc.description.abstract |
Colloids and Surfaces A: Physicochemical and Engineering Aspects |
ru_RU |
dc.description.abstract |
The synthesis and study of self-association and encapsulation ability of new low toxic conjugate of tetra-phenyleneoxypentylcalix[4]resorcinarene and methoxy-poly(ethylene glycole) (C 5 OPh-mPEG) were described.
The conjugate is characterized by 1 H, 13 C NMR, FT-IR, MS, SLS methods. In an aqueous solution the conjugate form multimicellar nanoparticles with low polydispersity value (0.1, DLS method). The self-association of the conjugate was studied by DLS, fluorescence, fluorescence anisotropy method, TEM, and SAXS methods. The SAXS data were detailed analyzed, and the conjugate associates structure as ellipsoidal core-shell particles was proposed. The encapsulation efficiency is a result of the affinity of the conjugate low rim substituents to substrates and reaches of 39.8, 26.7, and 28.9% toward naproxen, ibuprofen and doxorubicin drugs, respectively. |
ru_RU |
dc.language.iso |
ru |
ru_RU |
dc.subject |
Calix[4]resorcinarene |
ru_RU |
dc.subject |
PEG |
ru_RU |
dc.subject |
conjugation |
ru_RU |
dc.subject |
SAXS |
ru_RU |
dc.subject |
encapsulation |
ru_RU |
dc.title |
The novel calix[4]resorcinarene-PEG conjugate: Synthesis, self-association and encapsulation properties |
ru_RU |
dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|