| Форма представления | Тезисы и материалы конференций в зарубежных журналах и сборниках |
| Год публикации | 2019 |
| Язык | английский |
|
Кубышева Наиля Исхаковна, автор
|
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Eliseeva Tatyana , автор
Glukhova M. , автор
Izvolenskaya Marina , автор
Khaletskaya Olga , автор
Klimanov Igor , автор
Kolegova Tatyana , автор
Kurashina V , автор
Murakaeva L. , автор
Soodaeva Svetlana , автор
Tush Elena , автор
|
| Библиографическое описание на языке оригинала |
Klimanov, I. A., Soodaeva, S. K., Tush, E. V., Kubysheva, N. I., Izvolenskaya, M. N., Eliseeva, T. I., T.I. Kolegova, V.A. Kurashina, O.V. Khaletskaya, L.R. Murakaeva, Glukhova, M. V. (2019). Relationship between salivary markers of oxidative stress (OS) and different levels of control of bronchial asthma (BA). European Respiratory Journal 2019 54: PA1706. |
| Аннотация |
European Respiratory Journal 2019; 54: Suppl. 63 |
| Ключевые слова |
Biomarkers, asthma - mechanism, children |
| Название журнала |
European Respiratory Journal 2019; 54: Suppl. 63
|
| URL |
https://erj.ersjournals.com/content/54/suppl_63/PA1706.abstract |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=244535 |
| Файлы ресурса | |
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Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Кубышева Наиля Исхаковна |
ru_RU |
| dc.contributor.author |
Eliseeva Tatyana |
ru_RU |
| dc.contributor.author |
Glukhova M. |
ru_RU |
| dc.contributor.author |
Izvolenskaya Marina |
ru_RU |
| dc.contributor.author |
Khaletskaya Olga |
ru_RU |
| dc.contributor.author |
Klimanov Igor |
ru_RU |
| dc.contributor.author |
Kolegova Tatyana |
ru_RU |
| dc.contributor.author |
Kurashina V |
ru_RU |
| dc.contributor.author |
Murakaeva L. |
ru_RU |
| dc.contributor.author |
Soodaeva Svetlana |
ru_RU |
| dc.contributor.author |
Tush Elena |
ru_RU |
| dc.date.accessioned |
2019-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2019-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2019 |
ru_RU |
| dc.identifier.citation |
Klimanov, I. A., Soodaeva, S. K., Tush, E. V., Kubysheva, N. I., Izvolenskaya, M. N., Eliseeva, T. I., T.I. Kolegova, V.A. Kurashina, O.V. Khaletskaya, L.R. Murakaeva, Glukhova, M. V. (2019). Relationship between salivary markers of oxidative stress (OS) and different levels of control of bronchial asthma (BA). European Respiratory Journal 2019 54: PA1706. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=244535 |
ru_RU |
| dc.description.abstract |
European Respiratory Journal 2019; 54: Suppl. 63 |
ru_RU |
| dc.description.abstract |
Introduction: Nowedays more than half patients with BA have partly controlled and uncontrolled of disease despite modern strategies of therapy. One of possible reason of low control of BA may be increase of OS in patients with airway inflammation.
Aims: investigation of systemic parametrs of OS in children with different levels of control of BA.
Material and Methods: We investigate 145 children with BA, 83 boys and 62 girls, 5-17 years old ages, with controlled BA (n=92) and partly controlled and uncontrolled BA (n=53). Control group included 18 healthy children 5-15 years old. The quantitative indicators of OS such as maximum intensity of chemiluminescence (Imax) and S parametеrs in the saliva were evaluated.
Results: Patients with uncontrolled BA have high level salivary prooxidant activity - S parametеrs (59,4 ? 7,85) and Imax (3,10 ? 0,34) saliva higher, that healthy children (14,54 ? 1,66 and 1,23 ? 0,12 S and Imax respectively) and patients with controlled BA (8,44 ? 1,25 и 0,45 ? 0,07 S and Imax respectively), F = 39,13, р < 0,0001 for S and F = 51,70, р < 0,0001 for Imax. In healthy group Imax/S ratio was more higher (0,091 ? 0,009), that in patients with BA, р<0,001). In parallel, in group with controlled BA Imax/S ratio was lower (0,056 ? 0,002), that in uncontrolled patients (0,064 ? 0,003), p=0,0084. Decrease CL intensivity of saliva in patients with controlled BA may be the result of a decrease in OS tension.
Conclusion: We suppose, that CL parametrs of saliva can be used in assessment systemic OS in patients with BA and undirect estimation systemic aspects of allergic inflammation. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
Biomarkers |
ru_RU |
| dc.subject |
asthma - mechanism |
ru_RU |
| dc.subject |
children |
ru_RU |
| dc.title |
Relationship between salivary markers of oxidative stress (OS) and different levels of control of bronchial asthma (BA). |
ru_RU |
| dc.type |
Тезисы и материалы конференций в зарубежных журналах и сборниках |
ru_RU |
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