КФУ. Карточка публикации. Interpolyelectrolyte mixed nanoparticles from anionic and cationic thiacalix[4]arenes for selective recognition of model biopolymers

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INTERPOLYELECTROLYTE MIXED NANOPARTICLES FROM ANIONIC AND CATIONIC THIACALIX[4]ARENES FOR SELECTIVE RECOGNITION OF MODEL BIOPOLYMERS

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2019

Язык

английский

Авторы, сотрудники КФУ

Кунафина Айсылу Фависовна, автор

Нугманова Айгуль Рафилевна, автор

Осин Юрий Николаевич, автор

Падня Павел Леонидович, автор

Стойков Иван Иванович, автор

Якимова Людмила Сергеевна, автор

Библиографическое описание на языке оригинала

Yakimova, L. Interpolyelectrolyte mixed nanoparticles from anionic and cationic thiacalix[4]arenes for selective recognition of model biopolymers / L. Yakimova, P. Padnya, D. Tereshina, A. Nugmanova, A. Kunafina, Y. Osin, V. Evtugyn, I. Stoikov // Journal of Molecular Liquids. – 2019. – V. 279. – P. 9–17.

Аннотация

In this paper, we propose and develop an approach to synthesize an interpolyelectrolyte mixed nanoparticles of cationic and anionic thiacalix[4]arene derivatives, capable to selective recognition of model biopolymers (DNA from calf thymus, lysozyme, bovine serum albumin). Some ammonium and sulfonate derivatives of the p-tert-butylthiacalix[4]arene were chosen as supramolecular building blocks of these nanoparticles. In addition, we synthesized sulfobetaine-functionalized macrocycle where anionic and cationic groups are included in one molecular platform. Depending on conformation of macrocyclic platform (cone, 1,3-alternate) interpolyelectrolyte mixed nanoparticles with different size, stability and morphology were synthesized. We showed that the recognition of biopolymers is selective and depends on the ability to forming of nano-associates and the nature (charge) of the functional groups on the surface of the interpolyelectrolyte mixed nanoparticles. Negatively charged interpolyelectrolyte mixed nanoparticles form associates with lysozyme, while positively charged interpolyelectrolytes compact the high molecular DNA from calf thymus. The sulfobetaine derivatives of the thiacalix[4]arene stabilize monomeric form of BSA. ? 2019 Elsevier B.V.

Ключевые слова

Interpolyelectrolyte, nanoparticles, thiacalix[4]arenes, biopolymers

Название журнала

Journal of Molecular Liquids

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https://repository.kpfu.ru/?p_id=246059

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Кунафина Айсылу Фависовна	ru_RU
dc.contributor.author	Нугманова Айгуль Рафилевна	ru_RU
dc.contributor.author	Осин Юрий Николаевич	ru_RU
dc.contributor.author	Падня Павел Леонидович	ru_RU
dc.contributor.author	Стойков Иван Иванович	ru_RU
dc.contributor.author	Якимова Людмила Сергеевна	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	Yakimova, L. Interpolyelectrolyte mixed nanoparticles from anionic and cationic thiacalix[4]arenes for selective recognition of model biopolymers / L. Yakimova, P. Padnya, D. Tereshina, A. Nugmanova, A. Kunafina, Y. Osin, V. Evtugyn, I. Stoikov // Journal of Molecular Liquids. – 2019. – V. 279. – P. 9–17.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=246059	ru_RU
dc.description.abstract	Journal of Molecular Liquids	ru_RU
dc.description.abstract	In this paper, we propose and develop an approach to synthesize an interpolyelectrolyte mixed nanoparticles of cationic and anionic thiacalix[4]arene derivatives, capable to selective recognition of model biopolymers (DNA from calf thymus, lysozyme, bovine serum albumin). Some ammonium and sulfonate derivatives of the p-tert-butylthiacalix[4]arene were chosen as supramolecular building blocks of these nanoparticles. In addition, we synthesized sulfobetaine-functionalized macrocycle where anionic and cationic groups are included in one molecular platform. Depending on conformation of macrocyclic platform (cone, 1,3-alternate) interpolyelectrolyte mixed nanoparticles with different size, stability and morphology were synthesized. We showed that the recognition of biopolymers is selective and depends on the ability to forming of nano-associates and the nature (charge) of the functional groups on the surface of the interpolyelectrolyte mixed nanoparticles. Negatively charged interpolyelectrolyte mixed nanoparticles form associates with lysozyme, while positively charged interpolyelectrolytes compact the high molecular DNA from calf thymus. The sulfobetaine derivatives of the thiacalix[4]arene stabilize monomeric form of BSA. ? 2019 Elsevier B.V.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Interpolyelectrolyte	ru_RU
dc.subject	nanoparticles	ru_RU
dc.subject	thiacalix[4]arenes	ru_RU
dc.subject	biopolymers	ru_RU
dc.title	Interpolyelectrolyte mixed nanoparticles from anionic and cationic thiacalix[4]arenes for selective recognition of model biopolymers	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU