| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2020 |
| Язык | английский |
|
Зиганшина Альбина Юлдузовна, автор
|
| Библиографическое описание на языке оригинала |
Kashapov R. Supramolecular assembly of calix[4]resorcinarenes and chitosan for the design of drug nanocontainers with selective effects on diseased cells / R. Kashapov, Yu. Razuvayeva, A. Ziganshina, T. Sergeeva, N. Kashapova, A. Sapunova, A. Voloshina, I. Nizameev, V. Salnikov, L. Zakharova // New J. Chem. – 2020. – 44. – 17854-17863. |
| Аннотация |
In this paper, the spontaneous formation of nanoparticles through supramolecular interactions between chitosan and sulfonated calix[4]resorcinarenes was demonstrated. A set of physical–chemical methods were used to determine the ratio of components favorable for the formation of mixed aggregates, the size and the morphology of these aggregates formed in water solutions. The encapsulating and biological properties of the resulting chitosan–calix[4]resorcinarene compositions were studied. The stability of the obtained compositions with the encapsulated substrate was investigated over time. The cytotoxicity study showed their selective effect on the tumor cell line. The design pathway described here can be applied for the formation of various functional drug delivery systems comprising chitosan and macrocycles. |
| Ключевые слова |
calix[4]resorcinarene |
| Название журнала |
NEW JOURNAL OF CHEMISTRY
|
| URL |
https://pubs.rsc.org/en/content/articlelanding/2020/NJ/D0NJ02163F |
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=262824 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Зиганшина Альбина Юлдузовна |
ru_RU |
| dc.date.accessioned |
2020-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2020-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2020 |
ru_RU |
| dc.identifier.citation |
Kashapov R. Supramolecular assembly of calix[4]resorcinarenes and chitosan for the design of drug nanocontainers with selective effects on diseased cells / R. Kashapov, Yu. Razuvayeva, A. Ziganshina, T. Sergeeva, N. Kashapova, A. Sapunova, A. Voloshina, I. Nizameev, V. Salnikov, L. Zakharova // New J. Chem. – 2020. – 44. – 17854-17863. |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=262824 |
ru_RU |
| dc.description.abstract |
NEW JOURNAL OF CHEMISTRY |
ru_RU |
| dc.description.abstract |
In this paper, the spontaneous formation of nanoparticles through supramolecular interactions between chitosan and sulfonated calix[4]resorcinarenes was demonstrated. A set of physical–chemical methods were used to determine the ratio of components favorable for the formation of mixed aggregates, the size and the morphology of these aggregates formed in water solutions. The encapsulating and biological properties of the resulting chitosan–calix[4]resorcinarene compositions were studied. The stability of the obtained compositions with the encapsulated substrate was investigated over time. The cytotoxicity study showed their selective effect on the tumor cell line. The design pathway described here can be applied for the formation of various functional drug delivery systems comprising chitosan and macrocycles. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
|
ru_RU |
| dc.title |
Supramolecular assembly of calix[4]resorcinarenes and chitosan for the design of drug nanocontainers with selective effects on diseased cells |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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