КФУ. Карточка публикации. A Glucose‐Responsive Polymer Nanocarrier Based on Sulfonated Resorcinarene for Controlled Insulin Delivery

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A GLUCOSE‐RESPONSIVE POLYMER NANOCARRIER BASED ON SULFONATED RESORCINARENE FOR CONTROLLED INSULIN DELIVERY

Форма представления

Статьи в зарубежных журналах и сборниках

Год публикации

2019

Язык

русский

Авторы, сотрудники КФУ

Зиганшина Альбина Юлдузовна, автор

Библиографическое описание на языке оригинала

T. Yu. Sergeeva, R. K. Mukhitova, I. R. Nizameev, M. K. Kadirov, A. S. Sapunova, A. D. Voloshina, T. A. Mukhametzyanov, A. Y. Ziganshina, I. S. Antipin / A Glucose‐Responsive Polymer Nanocarrier Based on Sulfonated Resorcinarene for Controlled Insulin Delivery // ChemPlusChem. – 2019. – 84. – 1560-1566.

Аннотация

An insulin nanocarrier was synthesized by the microemulsion polymerization of sulfonated resorcinarenes with phenylboronic acid. The nanocarrier is stable at normal glucose levels, and it dissociates at a glucose concentration about 10 mM. The insulin encapsulation and release were investigated by NMR, UV, and fluorescence spectroscopy. An increase in glucose concentration from 5 to 10 mM leads to an increase in the insulin release from 10 to 100 %.

Ключевые слова

nanovarrier, insulin, glucose

Название журнала

ChemPlusChem

URL

https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cplu.201900428

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https://repository.kpfu.ru/?p_id=262888

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Зиганшина Альбина Юлдузовна	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	T. Yu. Sergeeva, R. K. Mukhitova, I. R. Nizameev, M. K. Kadirov, A. S. Sapunova, A. D. Voloshina, T. A. Mukhametzyanov, A. Y. Ziganshina, I. S. Antipin / A Glucose‐Responsive Polymer Nanocarrier Based on Sulfonated Resorcinarene for Controlled Insulin Delivery // ChemPlusChem. – 2019. – 84. – 1560-1566.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=262888	ru_RU
dc.description.abstract	ChemPlusChem	ru_RU
dc.description.abstract	An insulin nanocarrier was synthesized by the microemulsion polymerization of sulfonated resorcinarenes with phenylboronic acid. The nanocarrier is stable at normal glucose levels, and it dissociates at a glucose concentration about 10 mM. The insulin encapsulation and release were investigated by NMR, UV, and fluorescence spectroscopy. An increase in glucose concentration from 5 to 10 mM leads to an increase in the insulin release from 10 to 100 %.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	nanovarrier	ru_RU
dc.subject	insulin	ru_RU
dc.subject	glucose	ru_RU
dc.title	A Glucose‐Responsive Polymer Nanocarrier Based on Sulfonated Resorcinarene for Controlled Insulin Delivery	ru_RU
dc.type	Статьи в зарубежных журналах и сборниках	ru_RU