| Форма представления | Статьи в зарубежных журналах и сборниках |
| Год публикации | 2023 |
| Язык | английский |
|
Воробьев Владимир Николаевич, автор
|
| Библиографическое описание на языке оригинала |
Olga Petrova , Olga Parfirova , Natalia Gogoleva , Vladimir Vorob'ev , Yuri Gogolev and Vladimir Gorshkov.
The Role of Intercellular Signaling in the Regulation of Bacterial Adaptive Proliferation//Int. J. Mol. Sci. 2023, 24, 7266 |
| Аннотация |
International Journal of Molecular Sciences |
| Ключевые слова |
adaptive proliferation; intercellular communication; starvation stress; autoinducers; Pectobacterium atrosepticum; quorum sensing; cross-protection |
| Название журнала |
International Journal of Molecular Sciences
|
| Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на эту карточку |
https://repository.kpfu.ru/?p_id=279362 |
Полная запись метаданных  |
| Поле DC |
Значение |
Язык |
| dc.contributor.author |
Воробьев Владимир Николаевич |
ru_RU |
| dc.date.accessioned |
2023-01-01T00:00:00Z |
ru_RU |
| dc.date.available |
2023-01-01T00:00:00Z |
ru_RU |
| dc.date.issued |
2023 |
ru_RU |
| dc.identifier.citation |
Olga Petrova , Olga Parfirova , Natalia Gogoleva , Vladimir Vorob'ev , Yuri Gogolev and Vladimir Gorshkov.
The Role of Intercellular Signaling in the Regulation of Bacterial Adaptive Proliferation//Int. J. Mol. Sci. 2023, 24, 7266 |
ru_RU |
| dc.identifier.uri |
https://repository.kpfu.ru/?p_id=279362 |
ru_RU |
| dc.description.abstract |
International Journal of Molecular Sciences |
ru_RU |
| dc.description.abstract |
Bacterial adaptation is regulated at the population level with the involvement of intercellular communication (quorum sensing). When the population density is insufficient for adaptation under starvation, bacteria can adjust it to a quorum level through cell divisions at the expense of endogenous resources. This phenomenon has been described for the phytopathogenic bacterium Pectobacterium atrosepticum (Pba), and it is called, in our study, adaptive proliferation. An important attribute of adaptive proliferation is its timely termination, which is necessary to prevent the waste of endogenous resources when the required level of population density is achieved. However, metabolites that provide the termination of adaptive proliferation remained unidentified. We tested the hypothesis of whether quorum sensing-related autoinducers prime the termination of adaptive proliferation and assessed whether adaptive proliferation is a common phenomenon in the bacterial world. We showed that both known Pba quorum sensing-related autoinducers act synergistically and mutually compensatory to provide the timely termination of adaptive proliferation and formation of cross-protection. We also demonstrated that adaptive proliferation is implemented by bacteria of many genera and that bacteria with similar quorum sensing-related autoinducers have similar signaling backgrounds that prime the termination of adaptive proliferation, enabling the collaborative regulation of this adaptive program in multispecies communities. |
ru_RU |
| dc.language.iso |
ru |
ru_RU |
| dc.subject |
|
ru_RU |
| dc.title |
The Role of Intercellular Signaling in the Regulation of Bacterial Adaptive Proliferation |
ru_RU |
| dc.type |
Статьи в зарубежных журналах и сборниках |
ru_RU |
|
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