КФУ. Карточка публикации. Artificial microvesicles: new perspective on healing tendon wounds

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ARTIFICIAL MICROVESICLES: NEW PERSPECTIVE ON HEALING TENDON WOUNDS

Форма представления

Российские монографии

Год публикации

2022

Язык

андийский

Авторы, сотрудники КФУ

Аймалетдинов Александр Маазович, автор

Библиографическое описание на языке оригинала

Tendons have a limited capacity to repair both naturally and following clinical interventions. Damaged tissue often presents with structural and functional differences, adversely affecting animal performance, mobility, health and welfare. Advances in cell therapies have started to overcome some of these issues, however complications such as the formation of ectopic bone remain a complication of this technique. Regenerative medicine is therefore looking towards future therapies such as the introduction of microvesicles (MVs) derived from stem cells (SCs). The aim of the present study was to assess the characteristics of artificially derived MVs, from equine mesenchymal stem cells (MSCs), when delivered to rat tendon cells in vitro and damaged tendons in vivo. The initial stages of extracting MVs from equine MSCs and identifying and characterising the cultured tendon stem/progenitor cells (TSCs) from rat Achilles

Ключевые слова

Tendon, Stem/progenitor cell, Microvesicle, Differentiation, Membrane fusion

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https://repository.kpfu.ru/?p_id=284796

Полная запись метаданных

Поле DC	Значение	Язык
dc.contributor.author	Аймалетдинов Александр Маазович	ru_RU
dc.date.accessioned	2022-01-01T00:00:00Z	ru_RU
dc.date.available	2022-01-01T00:00:00Z	ru_RU
dc.date.issued	2022	ru_RU
dc.identifier.citation	Tendons have a limited capacity to repair both naturally and following clinical interventions. Damaged tissue often presents with structural and functional differences, adversely affecting animal performance, mobility, health and welfare. Advances in cell therapies have started to overcome some of these issues, however complications such as the formation of ectopic bone remain a complication of this technique. Regenerative medicine is therefore looking towards future therapies such as the introduction of microvesicles (MVs) derived from stem cells (SCs). The aim of the present study was to assess the characteristics of artificially derived MVs, from equine mesenchymal stem cells (MSCs), when delivered to rat tendon cells in vitro and damaged tendons in vivo. The initial stages of extracting MVs from equine MSCs and identifying and characterising the cultured tendon stem/progenitor cells (TSCs) from rat Achilles	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/?p_id=284796	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Tendon	ru_RU
dc.subject	Stem/progenitor cell	ru_RU
dc.subject	Microvesicle	ru_RU
dc.subject	Differentiation	ru_RU
dc.subject	Membrane fusion	ru_RU
dc.title	Artificial microvesicles: new perspective on healing tendon wounds	ru_RU
dc.type	Российские монографии	ru_RU